Unravelling cell migration: defining movement from the cell surface

F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

Extracellular matrix density regulates the formation of tumour spheroids through cell migration

IG Gonçalves, JM Garcia-Aznar - PLoS computational biology, 2021 - journals.plos.org
In this work, we show how the mechanical properties of the cellular microenvironment
modulate the growth of tumour spheroids. Based on the composition of the extracellular …

Hydrocolloids of egg white and gelatin as a platform for hydrogel-based tissue engineering

KG Pele, H Amaveda, M Mora, C Marcuello, A Lostao… - Gels, 2023 - mdpi.com
Innovative materials are needed to produce scaffolds for various tissue engineering and
regenerative medicine (TERM) applications, including tissue models. Materials derived from …

Three-dimensional analysis of hydrogel-imbedded aortic valve interstitial cell shape and its relation to contractile behavior

A Khang, Q Nguyen, X Feng, DP Howsmon, MS Sacks - Acta biomaterialia, 2023 - Elsevier
Cell-shape is a conglomerate of mechanical, chemical, and biological mechanisms that
reflects the cell biophysical state. In a specific application, we consider aortic valve interstitial …

[HTML][HTML] A mechanistic protrusive-based model for 3D cell migration

F Merino-Casallo, MJ Gomez-Benito… - European Journal of …, 2022 - Elsevier
Cell migration is essential for a variety of biological processes, such as embryogenesis,
wound healing, and the immune response. After more than a century of research—mainly on …

3D collagen migration patterns reveal a SMAD3-dependent and TGF-β1-independent mechanism of recruitment for tumour-associated fibroblasts in lung …

Y Juste-Lanas, N Díaz-Valdivia, A Llorente… - British Journal of …, 2023 - nature.com
Background The TGF-β1 transcription factor SMAD3 is epigenetically repressed in tumour-
associated fibroblasts (TAFs) from lung squamous cell carcinoma (SCC) but not …

3D collagen migration patterns reveal a SMAD3-dependent and TGF-ß1-independent mechanism of recruitment for tumour-associated fibroblasts in lung …

Y Juste-Lanas, A Bernardo, J Alcaraz, E Nadal… - 2023 - zaguan.unizar.es
Background: The TGF-β1 transcription factor SMAD3 is epigenetically repressed in tumour-
associated fibroblasts (TAFs) from lung squamous cell carcinoma (SCC) but not …

Hydrocolloids of Egg White and Gelatin as a Platform for Hydrogel-Based Tissue Engineering

S Pérez Huertas, K Georgiana Pele - 2023 - digibug.ugr.es
Innovative materials are needed to produce scaffolds for various tissue engineering and
regenerative medicine (TERM) applications, including tissue models. Materials derived from …

[PDF][PDF] Análisis del efecto de la matriz extracelular en la migración 3D de fibroblastos y osteoblastos humanos.

C Borau Zamora, JM García Aznar - 2021 - zaguan.unizar.es
Las células utilizan múltiples modos de migración para desplazarse en matrices
tridimensionales (3D), tanto de forma individual como colectiva, rigiéndose por la …

Computational Modelling of Cancer Systems: From Individual to Collective Cell Behaviour

MI Godinho Gonçalves, JM García Aznar - zaguan.unizar.es
Due to its complexity, cancer continues to be one of the leading causes of death worldwide.
The creation of suitable preventative practices and innovative therapies is limited by the lack …