In this work, we show how the mechanical properties of the cellular microenvironment modulate the growth of tumour spheroids. Based on the composition of the extracellular …
Innovative materials are needed to produce scaffolds for various tissue engineering and regenerative medicine (TERM) applications, including tissue models. Materials derived from …
Cell-shape is a conglomerate of mechanical, chemical, and biological mechanisms that reflects the cell biophysical state. In a specific application, we consider aortic valve interstitial …
Cell migration is essential for a variety of biological processes, such as embryogenesis, wound healing, and the immune response. After more than a century of research—mainly on …
Background The TGF-β1 transcription factor SMAD3 is epigenetically repressed in tumour- associated fibroblasts (TAFs) from lung squamous cell carcinoma (SCC) but not …
Background: The TGF-β1 transcription factor SMAD3 is epigenetically repressed in tumour- associated fibroblasts (TAFs) from lung squamous cell carcinoma (SCC) but not …
Innovative materials are needed to produce scaffolds for various tissue engineering and regenerative medicine (TERM) applications, including tissue models. Materials derived from …
Las células utilizan múltiples modos de migración para desplazarse en matrices tridimensionales (3D), tanto de forma individual como colectiva, rigiéndose por la …
Due to its complexity, cancer continues to be one of the leading causes of death worldwide. The creation of suitable preventative practices and innovative therapies is limited by the lack …