Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Bioactive Compounds of Filamentous Fungi with Biological Activity: a Systematic Review

RM de Matos, BVN Pereira… - … Gestão Social e …, 2023 - rgsa.openaccesspublications.org
Filamentous fungi are a rich source of bioactive compounds, which make them a promising
resource for the discovery of new drugs. Objective: The objective of this study was to …

Chemical constituents and antibacterial activity from the stems and leaves of Piper wallichii

C Nongmai, K Kanokmedhakul… - Journal of Asian …, 2022 - Taylor & Francis
A phytochemical investigation of the stems and leaves of Piper wallichii led to the isolation of
two new compounds, an aryl alkanone, piwalkanone (1) and a dioxoaporphine alkaloid …

Mass Spectrometry Guided Discovery and Design of Novel Asperphenamate Analogs From Penicillium astrolabium Reveals an Extraordinary NRPS Flexibility

K Subko, X Wang, FH Nielsen, T Isbrandt… - Frontiers in …, 2021 - frontiersin.org
Asperphenamate is a small peptide natural product that has gained much interest due to its
antitumor activity. In the recent years numerous bioactive synthetic asperphenamate …

In vitro nephrotoxicity and structure-toxicity relationships of eight natural aristolactams

S Xue, W Bao, J Lyu, C Wang, Y Zhang, H Li, D Chen… - Toxicon, 2025 - Elsevier
The structural similarity between aristolactams (ALs) and aristolochic acids (AAs) raises
constant concerns about the safety of ALs-containing plants. Natural ALs are distributed …

Aristolactam derivatives from Fissistigma glaucescens

YH Zhong, T Yin-Feng, XM Zhou, G Yan… - … Systematics and Ecology, 2021 - Elsevier
The phytochemical investigation of stems of Fissistigma glaucescens (Hance) Merr. led to
the isolation of a new aristolactam derivative aristolactam AIb (1), together with eleven …

HIV and the Role of Various Medicinal Plants Against Infection in Humans, with Possible Mechanism of Action and Functions of Secondary Metabolites

U Malik, D Pal - Anti-Viral Metabolites from Medicinal Plants, 2022 - Springer
Medicinal plants are always acceptable for their activity towards different disease targets as
they contain various extractable chemical constituents and bioactive metabolites. Plant …

[PDF][PDF] 天然马兜铃内酰胺的安全性和药理活性研究进展

武营雪, 刘静, 戴忠, 马双成 - 中国药学杂志, 2022 - journal11.magtechjournal.com
马兜铃内酰胺是具有菲内酰胺结构母核的一类化合物, 在自然界分布广泛,
同时也被认为是马兜铃酸在体内经硝基还原反应产生的代谢产物. 马兜铃酸类成分因马兜铃酸 …

Przeciwwirusowe związki izolowane z roślin

R Nawrot, A Warowicka, O Musidlak… - Postępy …, 2020 - postepybiochemii.ptbioch.edu.pl
Wirusy są wewnątrzkomórkowymi patogenami, które wykorzystują liczne procesy
komórkowe oraz białka i czynniki wirusowe do swojej replikacji. Obecnie nie ma …

[PDF][PDF] Przeciwwirusowe związki izolowane z roślin

A Warowicka, M Węglewska - researchgate.net
Wirusy są wewnątrzkomórkowymi patogenami, które wykorzystują liczne procesy
komórkowe oraz białka i czynniki wirusowe do swojej replikacji. Obecnie nie ma …