Congenital PAX6-aniridia, initially characterized by the absence of the iris, has progressively
been shown to be associated with other developmental ocular abnormalities and systemic …

Severe ocular surface disease can result in limbal stem cell deficiency (LSCD), a condition
leading to decreased visual acuity, photophobia, and ocular pain. To restore the ocular …

To treat unilateral limbal stem cell (LSC) deficiency, we developed cultivated autologous
limbal epithelial cells (CALEC) using an innovative xenobiotic-free, serum-free, antibiotic …

Background Amniotic membrane transplantation (AMT) has a long tradition in ophthalmic
surgery and has become very popular recently because of newly developed methods of …

In this report, we explore the biocompatibility of thermally-oxidised, aminosilanised porous
silicon membranes and their potential to support human ocular cells in vitro and in vivo, in …

Ocular stem cell transplantation derived from either autologous or allogeneic donor
corneoscleral junction is a functional cell therapy to manage extensive and/or severe limbal …

The cornea is the clear tissue at the front of the eye which enables the transmission of light
to the retina for normal vision. The surface of the cornea is composed of an epithelium which …

Human amniotic membrane (AM) is frequently used as a substrate for ocular surface
reconstruction. Its disadvantages (eg, reduced transparency and biomechanical strength …

The corneal epithelium is maintained by a population of stem cells known as limbal stem
cells (LSCs) due to their location in the basal layer of the outer border of the cornea known …

Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of
cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and …