Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

Immunoglobulin superfamily adhesion molecules are among the most abundant proteins in
vertebrate and invertebrate nervous systems. Prominent family members are the neural cell …

Accumulating data support the importance of interactions between pre-and postsynaptic
neuronal elements with astroglial processes and extracellular matrix (ECM) for formation …

Observations from different brain areas have established that the adult nervous system can
undergo significant experience-related structural changes throughout life. Less familiar is …

Many cell adhesion molecules are localized at synaptic sites in neuronal axons and
dendrites. These molecules bridge pre-and postsynaptic specializations but do far more …

Polysialic acid (PSA) is a cell-surface glycan with an enormous hydrated volume that serves
to modulate the distance between cells. This regulation has direct effects on several cellular …

This review presents principles of glycosylation, describes the relevant glycosylation
pathways and their related disorders, and highlights some of the neurological aspects and …

Neurogenesis in the adult dentate gyrus (DG) of the hippocampus occurs constitutively
throughout postnatal life, and the rate of neurogenesis within the DG can be altered under …

Polysialic acid (PSA) is a linear homopolymer of α2-8-N acetylneuraminic acid whose major
carrier in vertebrates is the neural cell adhesion molecule (NCAM). PSA serves as a potent …

The past 20 years witnessed an enormous leap in understanding of the central regulation of
whole-body energy metabolism. Genetic tools have enabled identification of the region …