Ca2+ signaling, genes and the cell cycle

K Machaca - Cell calcium, 2010 - Elsevier
Changes in the concentration and spatial distribution of Ca2+ ions in the cytoplasm
constitute a ubiquitous intracellular signaling module in cellular physiology. With the advent …

Calcium channels, external calcium concentration and cell proliferation

AS Borowiec, G Bidaux, N Pigat, V Goffin… - European journal of …, 2014 - Elsevier
Evidence for a role for calcium channel proteins in cell proliferation is numerous suggesting
that calcium influx is essential in this physiological process. Several studies in the past thirty …

Calcium influx-mediated signaling is required for complete mouse egg activation

YL Miao, P Stein, WN Jefferson… - Proceedings of the …, 2012 - National Acad Sciences
Mammalian fertilization is accompanied by oscillations in egg cytoplasmic calcium (Ca2+)
concentrations that are critical for completion of egg activation. These oscillations are …

The need for calcium channels in cell proliferation

T Capiod - Recent patents on anti-cancer drug discovery, 2013 - ingentaconnect.com
Both increases in the basal cytosolic calcium concentration ([Ca2+] cyt) and [Ca2+] cyt
transients play a major role in cell cycle progression, cell proliferation and division. Calcium …

Remodelling of the endoplasmic reticulum during store‐operated calcium entry

WW Shen, M Frieden, N Demaurex - Biology of the Cell, 2011 - Wiley Online Library
SOCE (store‐operated calcium entry) is a ubiquitous cellular mechanism linking the calcium
depletion of the ER (endoplasmic reticulum) to the activation of PM (plasma membrane) …

Regulation and role of store-operated Ca2+ entry in cellular proliferation

R Hodeify, F Yu, R Courjaret, N Nader… - … entry channels in non …, 2017 - taylorfrancis.com
This chapter presents a brief overview of the current knowledge as to the mechanisms
regulating store-operated Ca2+ entry (SOCE) during cell cycle from cellular proliferation to …

Extracellular calcium has multiple targets to control cell proliferation

T Capiod - Calcium Entry Pathways in Non-excitable Cells, 2016 - Springer
Calcium channels and the two G-protein coupled receptors sensing extracellular calcium,
calcium-sensing receptor (CaSR) and GPRC6a, are the two main means by which …

Remodeling of ER–plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis

F Yu, SZ Hubrack, S Chakraborty… - Proceedings of the …, 2019 - National Acad Sciences
Store-operated Ca2+ entry (SOCE), mediated by the endoplasmic reticulum (ER) Ca2+
sensor stromal interaction molecule 1 (STIM1) and the plasma membrane (PM) channel …

Termination of T cell priming relies on a phase of unresponsiveness promoting disengagement from APCs and T cell division

A Bohineust, Z Garcia, H Beuneu, F Lemaître… - Journal of Experimental …, 2018 - rupress.org
T cells are primed in secondary lymphoid organs by establishing stable interactions with
antigen-presenting cells (APCs). However, the cellular mechanisms underlying the …

[HTML][HTML] The STIM1 phosphorylation saga

F Yu, K Machaca - Cell Calcium, 2022 - Elsevier
Abstract Store-operated Ca 2+ entry (SOCE) is a Ca 2+ influx pathway present in practically
every cell type in metazoans and mediates a variety of physiological functions. Defects in …