The role of collagen-based biomaterials in chronic wound healing and sports medicine applications

DA Yeung, NH Kelly - Bioengineering, 2021 - mdpi.com
Advancements in tissue engineering have taken aim at treating tissue types that have
difficulty healing naturally. In order to achieve improved healing conditions, the balance of …

Amnion-derived hydrogels as a versatile platform for regenerative therapy: from lab to market

G Kafili, H Niknejad, E Tamjid, A Simchi - Frontiers in Bioengineering …, 2024 - frontiersin.org
In recent years, the amnion (AM) has emerged as a versatile tool for stimulating tissue
regeneration and has been of immense interest for clinical applications. AM is an abundant …

Comparative effectiveness of placental allografts in the treatment of diabetic lower extremity ulcers and venous leg ulcers in US Medicare beneficiaries: a retrospective …

WV Padula, S Ramanathan, BG Cohen… - Advances in Wound …, 2024 - liebertpub.com
Objective: To compare the effectiveness of cellular tissue products (CTP) versus standard
care in US Medicare beneficiaries with diabetic lower extremity ulcers (DLEUs) or venous …

Exosomes secreted from amniotic membrane contribute to its anti-fibrotic activity

Y Mao, V Jacob, A Singal, S Lei, MS Park… - International journal of …, 2021 - mdpi.com
Amniotic membranes (AM) have anti-fibrotic activity. Exosomes (nano-sized vesicles)
function as conduits for intercellular transfer and contain all the necessary components to …

Quantification of analgesic and anti-inflammatory lipid mediators in long-term cryopreserved and freeze-dried preserved human amniotic membrane

V Vrkoslav, I Smeringaiova, N Smorodinova… - Bioengineering, 2023 - mdpi.com
The aim of this study was to compare concentrations of endogenous N-acylethanolamine
(NAE) lipid mediators—palmitoylethanolamide (PEA), oleoylethanolamide (OEA), and …

Expert Revision of Key Elements for Clinical-Grade Production and Qualification of Perinatal Derivatives

R Gramignoli, N Hofmann… - Stem Cells …, 2024 - academic.oup.com
Perinatal derivatives have been proposed as adjunct therapeutic strategies or innovative
treatments. Undoubtedly, perinatal derivatives can offer the opportunity and source material …

Wound closure outcomes suggest clinical equivalency between lyopreserved and cryopreserved placental membranes containing viable cells

CE Ananian, RD Davis, EL Johnson… - Advances in Wound …, 2019 - liebertpub.com
Objective: To evaluate the clinical outcomes of lyopreserved placental membrane containing
viable cells (vLPM) in the treatment of nonhealing wounds of various etiologies, and to …

Comprehensive comparison of amnion stromal cells and chorion stromal cells by RNA-seq

B Jones, C Li, MS Park, A Lerch, V Jacob… - International Journal of …, 2021 - mdpi.com
Mesenchymal stromal cells derived from the fetal placenta, composed of an amnion
membrane, chorion membrane, and umbilical cord, have emerged as promising sources for …

A novel method to pack cryopreserved amniotic membrane for wound dressing—the pathway through validation of a new biological product

KS Ogliari, PB Grudzinski, CG da Silva… - Biomedical …, 2023 - iopscience.iop.org
Amniotic membrane (AM) has been widely used as a biological dressing for many
pathologies and illnesses worldwide, and products derived from this tissue have been …

A flowable placental formulation prevents bleomycin-induced dermal fibrosis in aged mice

S Dhall, A Lerch, N Johnson, V Jacob, B Jones… - International Journal of …, 2020 - mdpi.com
Fibrosis, the thickening and scarring of injured connective tissue, leads to a loss of organ
function. Multiple cell types, including T-cells, macrophages, fibrocytes, and fibroblasts …