TAE Platts-Mills - Journal of Allergy and Clinical Immunology, 2015 - Elsevier
Before the first description of hay fever in 1870, there was very little awareness of allergic disease, which is actually similar to the situation in prehygiene villages in Africa today. The …
CM Salome, GG King, N Berend - Journal of applied …, 2010 - journals.physiology.org
In obese people, the presence of adipose tissue around the rib cage and abdomen and in the visceral cavity loads the chest wall and reduces functional residual capacity (FRC). The …
Rationale: In patients with community-acquired pneumonia, guidelines recommend antibiotic treatment for 7 to 21 d. Procalcitonin is elevated in bacterial infections, and its …
Asthma and obesity are prevalent disorders, each with a significant public health impact, and a large and growing body of literature suggests an association between the two. The …
DC Doeing, J Solway - Journal of applied physiology, 2013 - journals.physiology.org
Airway smooth muscle (ASM) plays an integral part in the pathophysiology of asthma. It is responsible for acute bronchoconstriction, which is potentiated by constrictor …
SS An, TR Bai, JHT Bates, JL Black… - European …, 2007 - Eur Respiratory Soc
Excessive airway obstruction is the cause of symptoms and abnormal lung function in asthma. As airway smooth muscle (ASM) is the effecter controlling airway calibre, it is …
LM Schachter, CM Salome, JK Peat, AJ Woolcock - Thorax, 2001 - thorax.bmj.com
BACKGROUND A study was undertaken to assess whether the recent increases in prevalence of both asthma and obesity are linked and to determine if obesity is a risk factor …
E Von Mutius, J Schwartz, LM Neas, D Dockery… - Thorax, 2001 - thorax.bmj.com
BACKGROUND An increase in the prevalence of obesity and asthma over recent decades has been reported in affluent societies. Both overweight and obesity have been shown to be …
KM McClean, F Kee, IS Young, JS Elborn - Thorax, 2008 - thorax.bmj.com
Obesity is the most common metabolic disease in the world and its prevalence has been increasing over several decades. The World Health Organization (WHO) predicts that, by …