Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities
Inflammation has been convicted of causing and worsening many liver diseases like acute
liver failure, fibrosis, cirrhosis, fatty liver and liver cancer. Pattern recognition receptors …
liver failure, fibrosis, cirrhosis, fatty liver and liver cancer. Pattern recognition receptors …
[HTML][HTML] Autoimmune hepatitis: Towards a personalized treatment
A Costaguta, G Costaguta… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Autoimmune hepatitis is an uncommon condition that affects both adults and children and is
characterized by chronic and recurrent inflammatory activity in the liver. This inflammation is …
characterized by chronic and recurrent inflammatory activity in the liver. This inflammation is …
Escin suppresses immune cell infiltration and selectively modulates Nrf2/HO-1, TNF-α/JNK, and IL-22/STAT3 signaling pathways in concanavalin A-induced …
The current study aims to investigate the possible protective effect of escin, the active
constituent of a natural mixture of triterpene saponin glycoside, against immune-mediated …
constituent of a natural mixture of triterpene saponin glycoside, against immune-mediated …
Janus kinase inhibitor Tofacitinib alleviated acute hepatitis induced by lipopolysaccharide/D-galactosamine in mice
X Zhang, L Lin, L Li, K Hu, R Shao, L Zhang… - Molecular Biology …, 2023 - Springer
Abstract Background: The Janus kinase (JAK) is a crucial intracellular signaling hub for
numerous cytokines, which is extensively involved in the activation of inflammatory cascade …
numerous cytokines, which is extensively involved in the activation of inflammatory cascade …