Drug-induced liver injury and anti-hepatotoxic effect of herbal compounds: A metabolic mechanism perspective

J Rani, SB Dhull, PK Rose, MK Kidwai - Phytomedicine, 2024 - Elsevier
Background Drug-induced liver injury (DILI) is the most challenging and thought-provoking
liver problem for hepatologists owing to unregulated medication usage in medical practices …

Quality by design-driven zeta potential optimisation study of liposomes with charge imparting membrane additives

Z Németh, I Csóka, R Semnani Jazani, B Sipos… - Pharmaceutics, 2022 - mdpi.com
Liposomal formulations, as versatile nanocarrier systems suitable for targeted delivery, have
a highly focused role in the therapy development of unmet clinical needs and diagnostic …

[HTML][HTML] Liver-specific drug delivery platforms: applications for the treatment of alcohol-associated liver disease

JB Warner, SC Guenthner, JE Hardesty… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Alcohol-associated liver disease (ALD) is a common chronic liver disease and major
contributor to liver disease-related deaths worldwide. Despite its pre-valence, there are few …

Costunolide protects against alcohol‐induced liver injury by regulating gut microbiota, oxidative stress and attenuating inflammation in vivo and in vitro

J Mao, H Zhan, F Meng, G Wang, D Huang… - Phytotherapy …, 2022 - Wiley Online Library
Costunolide (cos) derived from the roots of Dolomiaea souliei (Franch.), which belongs to
the Dolomiaea genus in the family Compositae, exert the anti‐inebriation effect mainly by …

[HTML][HTML] The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

F Xiao, F Gao, S Zhou, L Wang - Medicine, 2020 - journals.lww.com
Background: To comprehensively evaluate the treatment efficacy and safety of silymarin for
patients with glucose/lipid metabolic dysfunction using a meta-analysis. Methods: A …

Characterization, optimization, and in vitro evaluation of cholesterol-free liposomes

AD Ergin, B Uner - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Objectives Alzheimer's disease (AD) is a neurological disorder that causes dementia and a
progressive loss of thinking, social, and memory abilities. Afterwards, this worsening induces …

Catechin ameliorates depressive symptoms in Sprague Dawley rats subjected to chronic unpredictable mild stress by decreasing oxidative stress Corrigendum in …

A Rai, M Gill, M Kinra, R Shetty… - Biomedical …, 2019 - spandidos-publications.com
Catechin is an active ingredient of green tea. It is reported to inhibit corticosteroid‑induced
anxiety and depression‑like symptoms. Considering the complex nature of depression …

[HTML][HTML] Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles on ethanol-induced hepatotoxicity in rats

AG Mahmoudabad, F Gheybi, M Mehrabi… - BioImpacts …, 2023 - ncbi.nlm.nih.gov
Synthesis, characterization and hepatoprotective effect of silymarin phytosome nanoparticles
on ethanol-induced hepatotoxicity in rats - PMC Back to Top Skip to main content NIH NLM …

Recapitulation of evidence of phytochemical, pharmacokinetic and biomedical application of silybin

A Islam, A Mishra, MA Siddiqui, S Siddiquie - Drug Research, 2021 - thieme-connect.com
Silymarin is a standardized extract obtained from seeds of Silybum marianum (SM)
belonging to the family Asteraceae. It is a flavonolignan complex and consists of various …

Liposomal nano-carriers mediated targeting of liver disorders: mechanisms and applications

MM AbouSamra - Journal of Liposome Research, 2024 - Taylor & Francis
Liver disorders present a significant global health challenge, necessitating the exploration of
innovative treatment modalities. Liposomal nanocarriers have emerged as promising …