Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …

Adipose tissue plays a central role in regulating whole-body energy and glucose
homeostasis through its subtle functions at both organ and systemic levels. On one hand …

Leptin and ghrelin are two hormones that have been recognized to have a major influence
on energy balance. Leptin is a mediator of long‐term regulation of energy balance …

Obesity is an escalating global chronic disease. Bariatric surgery is a very efficacious
treatment for obesity and its comorbidities. Alterations to gastrointestinal anatomy during …

Peripheral mechanisms in appetite regulation include the motor functions of the stomach,
such as the rate of emptying and accommodation, which convey symptoms of satiation to the …

Recent progress in the field of energy homeostasis was triggered by the discovery of
adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A …

Cholecystokinin and gastrin receptors (CCK1R and CCK2R) are G protein-coupled
receptors that have been the subject of intensive research in the last 10 years with …

Despite dramatic fluctuations in calorie intake, animals maintain a very stable body weight.
The reason is that energy intake and expenditure are precisely matched. Long-term …

Purpose: To evaluate leptin and leptin receptor (OB-R) expression in human breast cancer
and determine whether it could be effective for the prevention and treatment of breast …

Leptin, the protein product of the obese (ob or Lep) gene, is a hormone synthesized by
adipocytes that signals available energy reserves to the brain, and thereby influences …