Nucleic acid is the main material for storing, copying, and transmitting genetic information.
Gene sequencing is of great significance in DNA damage research, gene therapy, mutation …

There are currently no validated biomarkers which can be used to accurately diagnose
Alzheimer's disease (AD) or to distinguish it from other dementia-causing neuropathologies …

Alzheimer's disease (AD) is a chronic neurodegenerative disease characterized by the
progressive accumulation of amyloid-beta and neurofibrillary tangles of tau in the neocortex …

Neurodegenerative disorders are characterized by the progressive loss of central and/or
peripheral nervous system neurons. Within this context, neuroinflammation comes up as one …

Epigenome-wide association studies of Alzheimer's disease have highlighted
neuropathology-associated DNA methylation differences, although existing studies have …

Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …

Simple Summary DNA methylation is an epigenetic modification of genes which affects
corresponding gene expression. During the developmental stage, embryonic stem cells …

Aging, which is accompanied by decreased organ function and increased disease
incidence, limits human lifespan and has attracted investigators for thousands of years. In …

The gene based therapeutics and drug targets have shown incredible and appreciable
advances in alleviating human sufferings and complexities. Epigenetics simply means …

Background Alzheimer's disease is a progressive neurodegenerative disorder that is
hypothesized to involve epigenetic dysfunction. Previous studies of DNA modifications in …