Acute graft-versus-host disease

F Malard, E Holler, BM Sandmaier, H Huang… - Nature Reviews …, 2023 - nature.com
Acute graft-versus-host disease (GVHD) is a common immune complication that can occur
after allogeneic haematopoietic cell transplantation (alloHCT). Acute GVHD is a major …

Advancing cell-based cancer immunotherapy through stem cell engineering

YR Li, ZS Dunn, Y Yu, M Li, P Wang, L Yang - Cell Stem Cell, 2023 - cell.com
Advances in cell-based therapy, particularly CAR-T cell therapy, have transformed the
treatment of hematological malignancies. Although an important step forward for the field …

Guidelines on the Use of therapeutic apheresis in clinical practice–Evidence‐Based approach from the Writing Committee of the American Society for Apheresis: The …

L Connelly‐Smith, CR Alquist, NA Aqui… - Journal of clinical …, 2023 - Wiley Online Library
Abstract The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA)
Special Issue Writing Committee is charged with reviewing, updating, and categorizing …

[HTML][HTML] Ruxolitinib for glucocorticoid-refractory chronic graft-versus-host disease

R Zeiser, N Polverelli, R Ram, SK Hashmi… - … England Journal of …, 2021 - Mass Medical Soc
Background Chronic graft-versus-host disease (GVHD), a major complication of allogeneic
stem-cell transplantation, becomes glucocorticoid-refractory or glucocorticoid-dependent in …

How much has allogeneic stem cell transplant–related mortality improved since the 1980s? A retrospective analysis from the EBMT

O Penack, C Peczynski, M Mohty… - Blood …, 2020 - ashpublications.org
We performed a study to find out how advances in modern medicine have improved the
mortality risk of allogeneic stem cell transplantation. We analyzed major transplantation …

Posttransplant cyclophosphamide for prevention of graft-versus-host disease: results of the prospective randomized HOVON-96 trial

AEC Broers, CN de Jong, K Bakunina… - Blood …, 2022 - ashpublications.org
Graft-versus-host disease (GVHD) is the most important complication of allogeneic
hematopoietic stem cell transplantation (alloHSCT). We performed a prospective …

Mesenchymal stromal cells for the treatment of graft versus host disease

K Kelly, JEJ Rasko - Frontiers in immunology, 2021 - frontiersin.org
Graft versus host disease (GvHD) is a life-threating complication of allogeneic hematopoietic
stem cell transplantation, which is initially treated with high dose corticosteroids …

Recent FDA approvals in the treatment of graft-versus-host disease

DJ Martini, YB Chen, Z DeFilipp - The oncologist, 2022 - academic.oup.com
Graft-versus-host disease (GVHD) is a common complication of allogeneic hematopoietic
cell transplantation (HCT) and is associated with significant morbidity and mortality. For …

New approaches for the treatment of chronic graft-versus-host disease: current status and future directions

NEB Saidu, C Bonini, A Dickinson, M Grce… - Frontiers in …, 2020 - frontiersin.org
Chronic graft-versus-host disease (cGvHD) is a severe complication of allogeneic
hematopoietic stem cell transplantation that affects various organs leading to a reduced …

[HTML][HTML] Safety and tolerability of SARS-CoV2 emergency-use authorized vaccines for allogeneic hematopoietic stem cell transplant recipients

H Ali, D Ngo, A Aribi, S Arslan, S Dadwal… - … and cellular therapy, 2021 - Elsevier
The safety and efficacy of the severe acute respiratory syndrome coronavirus-2 (SARS-
CoV2) emergency-use authorized (EUA) vaccines have been confirmed in the general …