The cytolinker and scaffolding protein, plectin, has emerged as a potent driver of malignant
hallmarks in many human cancers due to its involvement in various cellular activities …

Replication-dependent histones are expressed in a cell cycle regulated manner and supply
the histones necessary to support DNA replication. In mammals, the replication-dependent …

The increasing popularity of iTRAQ for quantitative proteomics applications makes it
necessary to evaluate its relevance, accuracy, and precision for biological interpretation …

A major challenge in the management of patients with prostate cancer is identifying those
individuals at risk of developing metastatic disease, as in most cases the disease will remain …

Introduction Pre-eclampsia (PE), a severe pregnancy-specific disease characterized by the
new onset of hypertension, proteinuria, edema, and a series of other systematic disorders, is …

Background Cancer cachexia is observed in more than 50% of advanced cancer patients,
and impairs quality of life and prognosis. A variety of pathways are likely to be dysregulated …

In the last 15 years, increasing evidence linking epigenetics to various aspects of cancer
biology has prompted the investigation of histone post‐translational modifications (PTMs) …

Black and red rice are rich in both anthocyanin and proanthocyanin content, which belong to
a large class of flavonoids derived from a group of phenolic secondary metabolites …

Purpose Primary breast and prostate cancers can be cured, but metastatic disease cannot.
Identifying cell factors that predict metastatic potential could guide both prognosis and …

Background SM22 has long been studied as an actin-associated protein. Interestingly,
levels of SM22 are often reduced in tumour cell lines, while they are increased during …