Evidence on the health benefits of supplemental propolis

A Braakhuis - Nutrients, 2019 - mdpi.com
Propolis is a honey-related product with reported health benefits such as improved
immunity, lowered blood pressure, treated allergies and skin conditions. A literature review …

Pinocembrin: a novel natural compound with versatile pharmacological and biological activities

A Rasul, FM Millimouno, W Ali Eltayb… - BioMed research …, 2013 - Wiley Online Library
Pinocembrin (5, 7‐dihydroxyflavanone) is one of the primary flavonoids isolated from the
variety of plants, mainly from Pinus heartwood, Eucalyptus, Populus, Euphorbia, and …

Bee products: A representation of biodiversity, sustainability, and health

A Durazzo, M Lucarini, M Plutino, L Lucini, R Aromolo… - Life, 2021 - mdpi.com
Biodiversity strengthens the productivity of any ecosystem (agricultural land, forest, lake,
etc.). The loss of biodiversity contributes to food and energy insecurity; increases …

Pinocembrin inhibited cardiomyocyte pyroptosis against doxorubicin-induced cardiac dysfunction via regulating Nrf2/Sirt3 signaling pathway

J Gu, H Huang, C Liu, B Jiang, M Li, L Liu… - International …, 2021 - Elsevier
Doxorubicin (DOX) is a potent chemotherapeutic drug but the clinical use was limited by its
dose-dependent cardiotoxicity. Pinocembrin (PCB), a flavonoid originally isolated from …

Advances in biosynthesis, pharmacology, and pharmacokinetics of pinocembrin, a promising natural small-molecule drug

X Shen, Y Liu, X Luo, Z Yang - Molecules, 2019 - mdpi.com
Pinocembrin is one of the most abundant flavonoids in propolis, and it may also be widely
found in a variety of plants. In addition to natural extraction, pinocembrin can be obtained by …

The natural flavonoid pinocembrin: molecular targets and potential therapeutic applications

X Lan, W Wang, Q Li, J Wang - Molecular neurobiology, 2016 - Springer
Pinocembrin is a natural flavonoid compound extracted from honey, propolis, ginger roots,
wild marjoram, and other plants. In preclinical studies, it has shown anti-inflammatory and …

Plants‐derived neuroprotective agents: cutting the cycle of cell death through multiple mechanisms

TO Elufioye, TI Berida… - … and Alternative Medicine, 2017 - Wiley Online Library
Neuroprotection is the preservation of the structure and function of neurons from insults
arising from cellular injuries induced by a variety of agents or neurodegenerative diseases …

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling …

R Liu, C Wu, D Zhou, F Yang, S Tian, L Zhang, T Zhang… - BMC medicine, 2012 - Springer
Background It is known that amyloid-β peptide (Aβ) plays a pivotal role in the pathogenesis
of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation …

Kaempferol mediated AMPK/mTOR signal pathway has a protective effect on cerebral ischemic-reperfusion injury in rats by inducing autophagy

Y Yuan, F Xia, R Gao, Y Chen, Y Zhang, Z Cheng… - Neurochemical …, 2022 - Springer
Abstract Ischemia/reperfusion (I/R) caused by ischemic stroke treatments leads to brain
injury and its pathological mechanism is related to autophagy. The underlying mechanism of …

[HTML][HTML] Neuroprotective effects of pinocembrin on ischemia/reperfusion-induced brain injury by inhibiting autophagy

J Tao, C Shen, Y Sun, W Chen, G Yan - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Background Cerebral ischemia/reperfusion (I/R) injury is a common pathological process
after cardiac arrest, shock and acute cerebral infarction recanalization, which causes serious …