This comprehensive account of the human herpesviruses provides an encyclopedic
overview of their basic virology and clinical manifestations. This group of viruses includes …

Epstein–Barr virus (EBV) infection contributes to the development of several different types
of human malignancy, including Burkitt lymphoma, Hodgkin lymphoma, and …

Latency is a state of cryptic viral infection associated with genomic persistence and highly
restricted gene expression. Its hallmark is reversibility: under appropriate circumstances …

The general problem in cancer treatment centres on finding agents that specifically affect
cancer cells without damaging normal cells. The differences between cancer cells and …

In the last decade, the identification of enzymes that regulate acetylation of histones and
nonhistone proteins has revealed the key role of dynamic acetylation and deacetylation in …

Epstein–Barr virus (EBV) was first discovered in 1964, and was the first known human tumor
virus now shown to be associated with a vast number of human diseases. Numerous studies …

Background: Patients with rheumatoid arthritis or polymyositis treated with methotrexate
(MTX) develop Epstein–Barr virus (EBV)–positive lymphomas more frequently than patients …

ABSTRACT A novel therapy for Epstein-Barr virus (EBV)-positive tumors involves the
intentional induction of the lytic form of EBV infection combined with ganciclovir (GCV) …

Epstein-Barr virus, which mainly infects B cells and epithelial cells, has two modes of
infection: latent and lytic. Epstein-Barr virus infection is predominantly latent; however, lytic …

The apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like (APOBEC) family of
DNA cytosine deaminases provides a broad and overlapping defense against viral …