Cell-matrix interactions are fundamental to many developmental, homeostatic, immune and
pathologic processes. Hyaluronan (HA), a critical component of the extracellular matrix …

Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid
and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the …

The pathogenesis of bronchopulmonary dysplasia (BPD), a devastating lung disease in
preterm infants, includes inflammation, the mechanisms of which are not fully characterized …

Transition from homeostatic to reactive matrix remodeling is a fundamental adaptive tissue
response to injury, inflammatory disease, fibrosis, and cancer. Alterations in architecture …

OBJECTIVE: To determine whether a limited oxygen strategy (LOX) versus a high oxygen
strategy (HOX) during delivery room resuscitation decreases oxidative stress in preterm …

Over 50 years after its first description, Bronchopulmonary Dysplasia (BPD) remains a
devastating pulmonary complication in preterm infants with respiratory failure and develops …

Clinical and experimental data indicate that hyaluronan accumulates in breast cancer
compared with normal breast epithelium, which correlates to poor prognosis. In this review …

Acute lung injury results in early inflammation and respiratory distress, and later fibrosis. The
glycosaminoglycan hyaluronan (HA) and the Receptor for Hyaluronan-Mediated Motility …

Hyaluronic acid (HA) is a major component of the extracellular matrix. It is synthesized by
hyaluronan synthases (HAS) into high-molecular-weight chains (HMW-HA) that exhibit anti …

A buildup of reactive oxygen species (ROS) occurs in virtually all pathological conditions.
Hyaluronan (HA) is a major extracellular matrix component and is susceptible to oxidation …