Past, present, and future of affinity-based cell separation technologies

K Bacon, A Lavoie, BM Rao, M Daniele, S Menegatti - Acta biomaterialia, 2020 - Elsevier
Progress in cell purification technology is critical to increase the availability of viable cells for
therapeutic, diagnostic, and research applications. A variety of techniques are now available …

Manufacturing and banking of mesenchymal stem cells

S Thirumala, WS Goebel, EJ Woods - Expert opinion on biological …, 2013 - Taylor & Francis
Introduction: Mesenchymal stem cells (MSC) and MSC-like cells hold great promise and
offer many advantages for developing effective cellular therapeutics. Current trends indicate …

Characterizing the dielectric properties of human mesenchymal stem cells and the effects of charged elastin-like polypeptide copolymer treatment

TNG Adams, PA Turner, AV Janorkar, F Zhao… - …, 2014 - pubs.aip.org
Human mesenchymal stem cells (hMSCs) have three key properties that make them
desirable for stem cell therapeutics: differentiation capacity, trophic activity, and ability to self …

Separation technologies for stem cell bioprocessing

MM Diogo, CL da Silva… - Biotechnology and …, 2012 - Wiley Online Library
Stem cells have been the focus of an intense research due to their potential in Regenerative
Medicine, drug discovery, toxicology studies, as well as for fundamental studies on …

Allogeneic cell therapy manufacturing: process development technologies and facility design options

S Abbasalizadeh, M Pakzad, JMS Cabral… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Currently, promising outcomes from clinical trials of allogeneic cells, especially
allogeneic mesenchymal stromal cells, fibroblasts, keratinocytes, and human cardiac stem …

Production enhancement of human adipose-derived mesenchymal stem cells by low-intensity ultrasound stimulation

S Min, Y Byeon, M Kim, Y Lee, SH Lee, Y Lee… - Scientific Reports, 2022 - nature.com
Low-intensity ultrasound (LIUS) enhances the proliferation rate of various mammalian stem
cells through mechanical stimulation. This study quantitively finds suitable LIUS stimulation …

Aqueous two-phase systems strategies to establish novel bioprocesses for stem cells recovery

M González-González… - Critical reviews in …, 2014 - Taylor & Francis
During the past decade, stem cell transplantation has emerged as a novel therapeutic
alternative for several diseases. Nevertheless, numerous challenges regarding the recovery …

Stem cell bioprocessing for regenerative medicine

TG Fernandes, CAV Rodrigues… - Journal of Chemical …, 2014 - Wiley Online Library
Stem cell‐derived products have the potential to represent promising therapeutic
approaches for the treatment of a wide range of conditions. Neurodegenerative diseases …

[HTML][HTML] Emerging microfluidics-enabled platforms for osteoarthritis management: from benchtop to bedside

Z Zou, X Luo, Z Chen, YS Zhang, C Wen - Theranostics, 2022 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a prevalent debilitating age-related joint degenerative disease. It is a
leading cause of pain and functional disability in older adults. Unfortunately, there is no cure …

Design of large-scale manufacturing of induced pluripotent stem cell derived cardiomyocytes

CL Darkins, CF Mandenius - Chemical Engineering Research and Design, 2014 - Elsevier
A new approach for design of large-scale manufacture of stem cell derived cells by using the
biomechatronic methodology and computer-aided-design tools is described. The systematic …