Transition-metal-catalyzed C–H activation has developed a contemporary approach to the
omnipresent area of retrosynthetic disconnection. Scientific researchers have been tempted …

Due to their unique properties, fluorinated scaffolds are pivotal compounds in
pharmaceuticals, agrochemicals, and materials science. Over the last years, the …

We report the reprogramming of nonheme iron enzymes to catalyze an abiological C (sp3)‒
H azidation reaction through iron-catalyzed radical relay. This biocatalytic transformation …

A method of N-fluorocarboxamide-directed N-heterocyclic-carbene (NHC)-catalyzed
benzylic C–H acylation with aldehydes via the hydrogen atom transfer strategy is disclosed …

The review covers various aspects of fluorinated cycloalkyl (C3− C7) building blocks for drug
discovery, including their synthesis, key physicochemical properties, and biological and …

Despite the growing interest in the synthesis of fluorinated organic compounds, few
reactions are able to incorporate fluoride ions directly into alkyl C–H bonds. Here, we report …

We report the systematic development of an electrooxidative methodology that translates
stoichiometric C–H fluorination reactivity of an isolable Cu III fluoride complex into a catalytic …

We report, for the first time, a visible-light-promoted remote benzylic/aliphatic C (sp3)–H
heteroarylation of N-fluorocarboxamides with quinoxalin-2 (1H)-ones. This transformation …

In recent years there has been a surge in the development of methods for the synthesis of
organofluorine compounds. However, enzymatic methods for C–F bond formation have …

The iron-catalyzed δ-C (sp3)–H bond difluoromethylthiolation and difluoromethylselenation
of aliphatic amides with high site selectivity are reported. Essential to the success is the …