Transgene removal using an in cis programmed homing endonuclease via single-strand annealing in the mosquito Aedes aegypti
K Chae, B Contreras, JS Romanowski… - Communications …, 2024 - nature.com
While gene drive strategies have been proposed to aid in the control of mosquito-borne
diseases, additional genome engineering technologies may be required to establish a …
diseases, additional genome engineering technologies may be required to establish a …
Seamless knockins in Drosophila via CRISPR-triggered single-strand annealing
CRISPR-Cas greatly facilitated the integration of exogenous sequences into specific loci.
However, knockin generation in multicellular animals remains challenging, partially due to …
However, knockin generation in multicellular animals remains challenging, partially due to …
In vivo seamless genetic engineering via CRISPR-triggered single-strand annealing
Precise genome engineering is essential for both basic and applied research, permitting the
manipulation of genes and gene products in predictable ways. The irruption of the …
manipulation of genes and gene products in predictable ways. The irruption of the …
Genetic Dissection of DNA Damage Tolerance Mechanisms in Drosophila melanogaster
MX Tran - 2023 - search.proquest.com
DNA is frequently damaged by exogenous and endogenous sources. DNA base lesions can
block replicative DNA polymerases. These polymerases cannot efficiently use these …
block replicative DNA polymerases. These polymerases cannot efficiently use these …