Haemolytic uraemic syndrome

F Fakhouri, J Zuber, V Frémeaux-Bacchi, C Loirat - The Lancet, 2017 - thelancet.com
Haemolytic uraemic syndrome is a form of thrombotic microangiopathy affecting
predominantly the kidney and characterised by a triad of thrombocytopenia, mechanical …

Whole-genome sequencing of bacterial pathogens: the future of nosocomial outbreak analysis

S Quainoo, JPM Coolen, SAFT van Hijum… - Clinical microbiology …, 2017 - Am Soc Microbiol
Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient
populations in hospitals around the world. Intensive care unit (ICU) patients are particularly …

Nanopore sequencing for fast determination of plasmids, phages, virulence markers, and antimicrobial resistance genes in Shiga toxin-producing Escherichia coli

N Gonzalez-Escalona, MA Allard, EW Brown… - PLoS …, 2019 - journals.plos.org
Whole genome sequencing can provide essential public health information. However, it is
now known that widely used short-read methods have the potential to miss some randomly …

Detection, Characterization, and Typing of Shiga Toxin-Producing Escherichia coli

BD Parsons, N Zelyas, BM Berenger… - Frontiers in microbiology, 2016 - frontiersin.org
Shiga toxin-producing Escherichia coli (STEC) are responsible for gastrointestinal diseases
reported in numerous outbreaks around the world. Given the public health importance of …

Oxford nanopore sequencing in clinical microbiology and infection diagnostics

D Sheka, N Alabi, PMK Gordon - Briefings in bioinformatics, 2021 - academic.oup.com
Extended turnaround times and large economic costs hinder the usage of currently applied
screening methods for bacterial pathogen identification (ID) and antimicrobial susceptibility …

Rapid, multiplexed, whole genome and plasmid sequencing of foodborne pathogens using long-read nanopore technology

TL Taylor, JD Volkening, E DeJesus, M Simmons… - Scientific reports, 2019 - nature.com
US public health agencies have employed next-generation sequencing (NGS) as a tool to
quickly identify foodborne pathogens during outbreaks. Although established short-read …

Utility of whole-genome sequencing of Escherichia coli O157 for outbreak detection and epidemiological surveillance

A Holmes, L Allison, M Ward, TJ Dallman… - Journal of clinical …, 2015 - Am Soc Microbiol
Detailed laboratory characterization of Escherichia coli O157 is essential to inform
epidemiological investigations. This study assessed the utility of whole-genome sequencing …

Virulence gene profiles and phylogeny of Shiga toxin-positive Escherichia coli strains isolated from FDA regulated foods during 2010-2017

N Gonzalez-Escalona, JA Kase - Plos one, 2019 - journals.plos.org
Illnesses caused by Shiga toxin-producing Escherichia coli (STECs) can be life threatening,
such as hemolytic uremic syndrome (HUS). The STECs most frequently identified by USDA's …

[HTML][HTML] First step in using molecular data for microbial food safety risk assessment; hazard identification of Escherichia coli O157: H7 by coupling genomic data with in …

A Pielaat, MP Boer, LM Wijnands… - International Journal of …, 2015 - Elsevier
The potential for using whole genome sequencing (WGS) data in microbiological risk
assessment (MRA) has been discussed on several occasions since the beginning of this …

Characterization of Shiga toxin‐producing Escherichia coli isolated from Cattle and Sheep in Xinjiang province, China, using whole‐genome sequencing

Y Liu, H Li, X Chen, P Tong, Y Zhang… - Transboundary and …, 2022 - Wiley Online Library
Shiga toxin‐producing Escherichia coli (STEC) is an important food‐borne pathogen
capable of causing severe gastrointestinal diseases in humans. Cattle and sheep are the …