[HTML][HTML] Current research trends of nanomedicines

Q Liu, J Zou, Z Chen, W He, W Wu - Acta Pharmaceutica Sinica B, 2023 - Elsevier
Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate
therapeutic efficacy and toxicity in clinical treatment, nanomedicine designs have received …

A Safe‐by‐Design strategy towards safer nanomaterials in nanomedicines

L Yan, F Zhao, J Wang, Y Zu, Z Gu… - Advanced Materials, 2019 - Wiley Online Library
The marriage of nanotechnology and medicine offers new opportunities to fight against
human diseases. Benefiting from their unique optical, thermal, magnetic, or redox properties …

Size effect on the cytotoxicity of layered black phosphorus and underlying mechanisms

X Zhang, Z Zhang, S Zhang, D Li, W Ma, CX Ma, F Wu… - Small, 2017 - Wiley Online Library
A systematic cytotoxicity study of layered black phosphorus (BP) is urgently needed before
moving forward to its potential biomedical applications. Herein, bulk BP crystals are …

[HTML][HTML] Photocatalytic nanoparticles–from membrane interactions to antimicrobial and antiviral effects

E Parra-Ortiz, M Malmsten - Advances in colloid and interface science, 2022 - Elsevier
As a result of increasing resistance among pathogens against antibiotics and anti-viral
therapeutics, nanomaterials are attracting current interest as antimicrobial agents. Such …

Graphene-induced pore formation on cell membranes

G Duan, Y Zhang, B Luan, JK Weber, RW Zhou… - Scientific Reports, 2017 - nature.com
Examining interactions between nanomaterials and cell membranes can expose underlying
mechanisms of nanomaterial cytotoxicity and guide the design of safer nanomedical …

Understanding interactions between biomolecules and two-dimensional nanomaterials using in silico microscopes

SH Chen, DR Bell, B Luan - Advanced drug delivery reviews, 2022 - Elsevier
Abstract Two-dimensional (2D) nanomaterials such as graphene are increasingly used in
research and industry for various biomedical applications. Extensive experimental and …

Physico-Chemical Approaches to Investigate Surface Hydroxyls as Determinants of Molecular Initiating Events in Oxide Particle Toxicity

C Pavan, R Santalucia, G Escolano-Casado… - International Journal of …, 2023 - mdpi.com
The study of molecular recognition patterns is crucial for understanding the interactions
between inorganic (nano) particles and biomolecules. In this review we focus on hydroxyls …

Lipophilicity of cationic ligands promotes irreversible adsorption of nanoparticles to lipid bilayers

CA Lochbaum, AK Chew, X Zhang, V Rotello… - ACS …, 2021 - ACS Publications
A mechanistic understanding of the influence of the surface properties of engineered
nanomaterials on their interactions with cells is essential for designing materials for …

Emerging investigator series: interactions of engineered nanomaterials with the cell plasma membrane; what have we learned from membrane models?

AM Farnoud, S Nazemidashtarjandi - Environmental Science: Nano, 2019 - pubs.rsc.org
With the increasing industrial and biomedical applications of engineered nanomaterials
(ENMs), concerns have been raised regarding the increased risk of exposure. Exposure to …

Natural organic matter concentration impacts the interaction of functionalized diamond nanoparticles with model and actual bacterial membranes

AC Mensch, RT Hernandez, JE Kuether… - … science & technology, 2017 - ACS Publications
Changes to nanoparticle surface charge, colloidal stability, and hydrodynamic properties
induced by interaction with natural organic matter (NOM) warrant consideration in assessing …