Plants use molecular mechanisms mediated by biomolecular condensates to integrate environmental cues with development

S Field, GJ Jang, C Dean, LC Strader, SY Rhee - The Plant Cell, 2023 - academic.oup.com
This review highlights recent literature on biomolecular condensates in plant development
and discusses challenges for fully dissecting their functional roles. Plant developmental …

Advanced imaging techniques for studying protein phase separation in living cells and at single-molecule level

G Mekonnen, N Djaja, X Yuan, S Myong - Current Opinion in Chemical …, 2023 - Elsevier
Protein-protein and protein-RNA interactions are essential for cell function and survival.
These interactions facilitate the formation of ribonucleoprotein complexes and biomolecular …

The roles of FUS-RNA binding domain and low complexity domain in RNA-dependent phase separation

LR Ganser, AG Niaki, X Yuan, E Huang, D Deng… - Structure, 2024 - cell.com
Fused in sarcoma (FUS) is an archetypal phase separating protein asymmetrically divided
into a low complexity domain (LCD) and an RNA binding domain (RBD). Here, we explore …

[HTML][HTML] Current Opinion in Chemical Biology: Issue: Chemical Biology of Protein Aggregation and phase separation

G Mekonnen, N Djaja, X Yuan… - Current opinion in …, 2023 - pmc.ncbi.nlm.nih.gov
Protein-protein and protein-RNA interactions are essential for cell function and survival.
These interactions facilitate the formation of ribonucleoprotein (RNP) complexes and …

ALS/FTLD-Linked Mutant FUS Oligomerization in Cells

NA Djaja - 2024 - jscholarship.library.jhu.edu
Fused in sarcoma (FUS) is a nuclear RNA-binding protein (RBP) implicated in amyotrophic
lateral sclerosis (ALS) and frontotemporal lobar dementia (FTLD). FUS plays essential roles …