Genomic safe harbors (GSHs) are sites in the genome able to accommodate the integration
of new genetic material in a manner that ensures that the newly inserted genetic elements:(i) …

Here, the literature was reviewed to evaluate whether a population of mesenchymal stromal
cells derived from Wharton's jelly cells (WJCs) is a primitive stromal population. A clear case …

Defects in articular cartilage ultimately result in loss of joint function. Repairing cartilage
defects requires cell sources. We developed an approach to generate scaffoldless hyaline …

Embryonic stem (ES) cells are promising for cardiac repair'but directing their differentiation
toward cardiomyocytes remains challenging. We investigated whether the heart guides ES …

Tissue engineering is a newly emerging biomedical technology, which aids and increases
the repair and regeneration of deficient and injured tissues. It employs the principles from …

Substantial evidence indicates that cell transplantation can improve function of the infarcted
heart. A surprisingly wide range of non-myogenic cell types improves ventricular function …

Purpose To provide a comprehensive overview of the basic science and clinical evidence
behind cartilage regeneration techniques as they relate to surgical management of chondral …

Recent studies suggest that human adipose tissue contains pluripotent stem cells, which are
similar to bone marrow-derived stem cells. The objective of the present study was to assess …

The field of tissue engineering promises to deliver biological substitutes to repair or replace
tissues in the body that have been injured or diseased. The clinical demand for …

Osteoarthritis in the knees, which can be caused by meniscal defect, constitutes an
increasingly common medical problem. Repair for massive meniscal defect remains a …