The translocon protein FtsHi1 is an ATP‐dependent DNA/RNA helicase that prevents R‐loop accumulation in chloroplasts

X Chai, X Wang, L Rong, M Luo, L Yuan, Q Li… - New …, 2024 - Wiley Online Library
R‐loops, three‐stranded nucleic acid structures consisting of a DNA: RNA hybrid and
displaced single‐stranded DNA, play critical roles in gene expression and genome stability …

A positively charged surface patch on the pestivirus NS3 protease module plays an important role in modulating NS3 helicase activity and virus production

F Zheng, W Yi, W Liu, H Zhu, P Gong, Z Pan - Archives of Virology, 2021 - Springer
Abstract Pestivirus nonstructural protein 3 (NS3) is a multifunctional protein with protease
and helicase activities that are essential for virus replication. In this study, we used a …

Hierarchical assessment of host factors influencing the spontaneous resolution of hepatitis C infection

PJS Provazzi, LMG Rossi, BM Carneiro… - Brazilian Journal of …, 2019 - Springer
Abstract Background Hepatitis C virus (HCV) infection is associated with chronic liver
disease, resulting in cirrhosis and hepatocellular carcinoma. Approximately 20% of HCV …

[引用][C] Frequência de polimorfismos e mutações de resistência nos genes NS3, NS5A E NS5B e barreira genética aos antivirais de ação direta em sequências …

DA Kliemann - 2016