[HTML][HTML] Role of serotonin receptor signaling in cancer cells and anti-tumor immunity

S Karmakar, G Lal - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Serotonin or 5-hydroxytryptamine (5-HT) is a neurotransmitter known to affect
emotion, behavior, and cognition, and its effects are mostly studied in neurological diseases …

Serotonin pathway in cancer

P Balakrishna, S George, H Hatoum… - International journal of …, 2021 - mdpi.com
Serotonin (5-hydroxytryptamine, 5-HT) is a biogenic monoamine produced from the
essential amino acid tryptophan. Serotonin's role as a neurotransmitter in the central …

Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions

P Jayachandran, F Battaglin, C Strelez, A Lenz… - Oncogene, 2023 - nature.com
Exploring the relationship between various neurotransmitters and breast cancer cell growth
has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters …

The Expression of Trace Amine-Associated Receptors (TAARs) in Breast Cancer Is Coincident with the Expression of Neuroactive Ligand–Receptor Systems and …

AN Vaganova, DD Maslennikova, VV Konstantinova… - Biomolecules, 2023 - mdpi.com
Currently, the contribution of trace amine-associated receptors (TAARs) to breast cancer
(BC) is recognized, but their associations with various pathological characteristics are not …

Synthesis and Biological Evaluation of Peripheral HTR2A Antagonists for Colorectal Cancer

M Kim, J Yoon, JY Choi, G Park, JE Lee… - Journal of Medicinal …, 2025 - ACS Publications
Colorectal cancer is a prevalent and prominent contributor to global cancer-related fatalities
with challenges in drug resistance and metastasis. Recent research highlights the potential …

HTR3A Promotes Non-small Cell Lung Cancer Through the FOXH1/Wnt3A Signaling Pathway

Z Wu, J Li, M Zhong, Z Xu, M Yang, C Xu - Biochemical Genetics, 2024 - Springer
Hydroxytryptamine receptors (5-HTRs) are strongly correlated with tumor progression in
various types of cancer. Despite this, the underlying mechanisms responsible for the role of …

Serotonin 5-HT7 receptor is a biomarker poor prognostic factor and induces proliferation of triple-negative breast cancer cells through FOXM1

V Cınar, Z Hamurcu, A Guler, N Nurdinov, B Ozpolat - Breast Cancer, 2022 - Springer
Background Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer
and associated with poor prognosis and shorter survival due to significant genetic …

[HTML][HTML] Association between antipsychotic agents and risk of lung cancer: a nested case‐control study

J Li, F Tang, S Si, F Xue - Cancer Communications, 2022 - ncbi.nlm.nih.gov
Dear Editor, Antipsychotics are a class of psychotropic medication primarily used for the
treatment of schizophrenia and a range of other psychotic disorders. They are antagonists of …

Metabolomic Signatures of Scarff–Bloom–Richardson (SBR) Grade in Non-Metastatic Breast Cancer

C Bailleux, D Chardin, J Gal, JM Guigonis… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is a heterogeneous disease with multiple biological,
molecular, and histological subtypes. Several metabolomics studies have been performed …

Differential expression analysis of dopamine receptor genes Drd2, Drd3 and Drd4 in the tumoral and tumor margin samples of breast cancer patients

A Mirzaghasab, G Rigi - Biomacromolecular Journal, 2020 - bmmj.org
Cancer is one of the major causes of mortality in the world, and breast cancer is one of the
most common types of cancer affecting adult women. Various neurotransmitters may …