Sexual function, and testosterone (T) levels, progressively decline in aging men. Associated
morbidities and metabolic disorders can accelerate the phenomenon. The specific …

Erectile dysfunction is a common disease of the male reproductive system, which seriously
affects the life quality of patients and their partners. At present, erectile dysfunction is …

Background At midlife and beyond, both men and women face organic changes that can
affect sexual functioning. For women, ovarian exhaustion causes estrogen deficiency …

Phosphodiesterases (PDEs) consisted of 11 subtypes (PDE1 to PDE11) and over 40
isoforms that regulate levels of cyclic guanosine monophosphate (cGMP) and cyclic …

A dichotomic distinction between “organic” and “functional” hypogonadism is emerging. The
former is an irreversible condition due to congenital or “acquired”“organic” damage of the …

Objective The primary objectives were to compare the efficacy of extracts of the plant
Tribulus terrestris (TT; marketed as Tribestan), in comparison with placebo, for the treatment …

Background: Sexual dysfunction affects millions of people with an increasing prevalence,
worldwide. The pathophysiology of the disease shares several similarities with …

Purpose Infertility represents a peculiar social burden affecting more than 15% of couples,
provoking it a real threat to the general quality of life and to the sexual health. The …

Sexual health is an integral part of overall health, and an active and healthy sexual life is an
essential aspect of a good life quality. Cardiovascular disease and sexual health share …

The discontinuation rate with phosphodiesterase type 5 inhibitors (PDE 5i) remains very
high. The aim of this study was to review and meta‐analyze currently available data …