Roseburia intestinalis is an anaerobic, Gram-positive, slightly curved rod-shaped flagellated
bacterium that produces butyrate in the colon. R. intestinalis has been shown to prevent …

The intestinal surface is constitutively exposed to diverse antigens, such as food antigens,
food-borne pathogens, and commensal microbes. Intestinal epithelial cells have developed …

Host–microbiota interactions are fundamental for the development of the immune system.
Drastic changes in modern environments and lifestyles have led to an imbalance of this …

Approximately 5% of the world-wide population is affected by autoimmune diseases.
Overall, autoimmune diseases are still difficult to treat, impose a high burden on patients …

The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

Systemic lupus erythematosus (SLE), often considered the prototype of autoimmune
diseases, is characterized by over-activation of the autoimmune system with abnormal …

The presence of disease-specific autoantibody responses and the efficacy of B cell-targeting
therapies in rheumatoid arthritis (RA) indicate a pivotal role for B cells in disease …

INTRODUCTION Antiphospholipid antibodies (aPLs) transiently appear in infectious
diseases but can persist in primary antiphospholipid syndrome (APS) or in association with …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that was traditionally
thought to be closely related to genetic and environmental risk factors. Although treatment …