Retroviruses have evolved effective strategies to evade the host immune response, such as
high variability and latent infection. In addition, primate lentiviruses, such as HIV-1, have …

This article provides an overview and reviews the HIV pandemic, the basic biology and
immunology of the virus (eg, genetic diversity of HIV and the viral life cycle), the phases of …

There is considerable HIV-1 variation in patients. The extent of the variation is due to the
high rate of viral replication, the high viral load, and the errors made during viral replication …

Vpu proteins of pandemic HIV-1 M strains degrade the viral receptor CD4 and antagonize
human tetherin to promote viral release and replication. We show that Vpus from SIVgsn …

Early diagnosis and treatment of human immunodeficiency virus type 1 (HIV-1) infection in
infants can greatly reduce mortality rates. However, current infant HIV-1 diagnostics cannot …

The persistence of transcriptionally silent but replication-competent HIV-1 reservoirs in
Highly Active Anti-Retroviral Therapy (HAART)-treated infected individuals, represents a …

BACKGROUND: Previously, we presented evidence that at physiologic concentrations the
green tea catechin, epigallocatechin gallate (EGCG), inhibited attachment of HIV-1 …

Abstract Latin America and the Caribbean (LAC) is a region with similarities and important
disparities. In recent years LAC has witnessed achievements, with HIV prevalence rates …

Zoonotic events of simian immunodeficiency virus (SIV) from non-human primates to
humans have generated the acquired immunodeficiency syndrome (AIDS), one of the most …

Rabbit haemorrhagic disease (RHD) is a highly fatal disease caused by a virus of the family
Caliciviridae. Whereas recombination is well documented in other members of this family …