Psychobiotics—live microorganisms with potential mental health benefits, which can
modulate the microbiota-gut-brain-axis via immune, humoral, neural, and metabolic …

Abstract 'Dominant mutations in CAMK2B, encoding a subunit of the calcium/calmodulin-
dependent protein kinase II (CAMK2), a serine/threonine kinase playing a key role in …

The calcium/calmodulin-dependent protein kinase type 2 (CAMK2) family consists of four
different isozymes, encoded by four different genes—CAMK2A, CAMK2B, CAMK2G, and …

Depressive disorders (DDs) are an increasingly common health problem that affects all age
groups. DDs pathogenesis is multifactorial. However, it was proven that stress is one of the …

Glutamatergic synapses harbor abundant amounts of the multifunctional Ca2+/calmodulin-
dependent protein kinase type II (CaMKII). Both in the postsynaptic density as well as in the …

Kaposi's sarcoma-associated herpesvirus (KSHV) causes several human diseases
including Kaposi's sarcoma (KS), a leading cause of cancer in Africa and in patients with …

Highlights•CAMK2 related disorders are caused by pathological variants in all four
paralogs.•The vast majority of CAMK2 variants are unique missense variants.•Despite …

Introduction The gamma subunit of calcium/calmodulin-dependent protein kinase 2
(CAMK2G) is expressed throughout the brain and is associated with neurodevelopmental …

CaMKIIα plays a fundamental role in learning and memory and is a key determinant of
synaptic plasticity. Its kinase activity is regulated by the binding of Ca2+/CaM and by …

Cognitive impairment refers to abnormalities in learning, memory and cognitive judgment,
mainly manifested as symptoms such as decreased memory, impaired orientation and …