Highlights•MDR P. aeruginosa is one of the major causes of the nosocomial
infections.•Virulence factors involved in pathogenicity were described.•Potential inhibitors of …

Combination antibiotic therapy for invasive infections with Gram-negative bacteria is
employed in many health care facilities, especially for certain subgroups of patients …

Background Increasing rates of resistant and multidrug-resistant (MDR) P. aeruginosa in
hospitalized patients constitute a major public health threat. We present a systematic review …

Ventilator-associated pneumonia (VAP) continues to complicate the course of 8 to 28% of
patients receiving mechanical ventilation (MV). In contrast to infections of more frequently …

Burns are one of the most common and devastating forms of trauma. Patients with serious
thermal injury require immediate specialized care in order to minimize morbidity and …

Rates of antibiotic resistance in Pseudomonas aeruginosa are increasing worldwide. The
multidrug-resistant (MDR) phenotype in P. aeruginosa could be mediated by several …

Abstract The Antimicrobial Availability Task Force (AATF) of the Infectious Diseases Society
of America (IDSA) has viewed with concern the decreasing investment by major …

Abstract Background Urinary tract infections (UTIs) remain the common infections diagnosed
in outpatients as well as hospitalized patients. Current knowledge on antimicrobial …

Aminoglycoside antibiotics have had a major impact on our ability to treat bacterial infections
for the past half century. Whereas the interest in these versatile antibiotics continues to be …

During the last decade, the efforts to combat multidrugresistant (MDR) microorganisms
mainly focused on gram-positive bacteria, namely, methicillin-resistant Staphylococcus …