Emerging materials for hemostasis
Severe hemorrhage has posed a serious threat to the health and even life of civilian and
military populations and brought serious economic losses. Consequently, it is imperative to …
military populations and brought serious economic losses. Consequently, it is imperative to …
Effects of the COVID-19 pandemic on supply and use of blood for transfusion
SJ Stanworth, HV New, TO Apelseth… - The Lancet …, 2020 - thelancet.com
The COVID-19 pandemic has major implications for blood transfusion. There are uncertain
patterns of demand, and transfusion institutions need to plan for reductions in donations and …
patterns of demand, and transfusion institutions need to plan for reductions in donations and …
Platelets and their biomimetics for regenerative medicine and cancer therapies
Platelets, circulating blood cells derived from megakaryocytes, play a key role in various
physical activities, including coagulation, hemostasis, the body's innate immune response …
physical activities, including coagulation, hemostasis, the body's innate immune response …
Whole blood transfusion
Whole blood is the preferred product for resuscitation of severe traumatic hemorrhage. It
contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in …
contains all the elements of blood that are necessary for oxygen delivery and hemostasis, in …
A pilot trial of platelets stored cold versus at room temperature for complex cardiothoracic surgery
G Strandenes, J Sivertsen, CK Bjerkvig… - …, 2020 - ingentaconnect.com
Background: This pilot trial focused on feasibility and safety to provide preliminary data to
evaluate the hemostatic potential of cold-stored platelets (2° to 6° C) compared with …
evaluate the hemostatic potential of cold-stored platelets (2° to 6° C) compared with …
Refrigeration and cryopreservation of platelets differentially affect platelet metabolism and function: a comparison with conventional platelet storage conditions
BACKGROUND Alternatives to room temperature storage of platelets (PLTs) may be
beneficial to extend the limited shelf life and support transfusion logistics in rural and military …
beneficial to extend the limited shelf life and support transfusion logistics in rural and military …
Damage control resuscitation
Damage control resuscitation (DCR) is a strategy for resuscitating patients from hemorrhagic
shock to rapidly restore homeostasis. Efforts are focused on blood product transfusion with …
shock to rapidly restore homeostasis. Efforts are focused on blood product transfusion with …
Platelets stored at 4° C contribute to superior clot properties compared to current standard‐of‐care through fibrin‐crosslinking
PM Nair, SG Pandya, SF Dallo… - British journal of …, 2017 - Wiley Online Library
Currently, platelets for transfusion are stored at room temperature (RT) for 5–7 days with
gentle agitation, but this is less than optimal because of loss of function and risk of bacterial …
gentle agitation, but this is less than optimal because of loss of function and risk of bacterial …
Cold platelets for trauma‐associated bleeding: regulatory approval, accreditation approval, and practice implementation—just the “tip of the iceberg”
JR Stubbs, SA Tran, RL Emery, SA Hammel… - …, 2017 - Wiley Online Library
BACKGROUND Laboratory and clinical evidence suggest that cold‐stored platelets (CS‐
PLTs) might be preferable to room temperature platelets (RT‐PLTs) for active bleeding …
PLTs) might be preferable to room temperature platelets (RT‐PLTs) for active bleeding …
Cold-stored platelets: A product with function optimized for hemorrhage control
KM Reddoch-Cardenas, JA Bynum… - … and Apheresis Science, 2019 - Elsevier
Early administration of blood products following severe trauma is pivotal for establishing
hemostasis and achieving successful outcomes. Platelet transfusions, in particular, provide …
hemostasis and achieving successful outcomes. Platelet transfusions, in particular, provide …