Alteration of the chromatin orchestra seems to play a critical role in cancer. In recent years,
in-depth studies of epigenetic machinery and its deregulation have led to the development …

Neuroplasticity is a crucial property of the central nervous system to change its activity in
response to intrinsic or extrinsic stimuli. This is mainly achieved through the promotion of …

Lichens are valuable natural resources used for centuries throughout the world as medicine,
food, fodder, perfume, spices and dyes, as well as for other miscellaneous purposes. This …

The class I histone deacetylases are essential regulators of cell fate decisions in health and
disease. While pan-and class-specific HDAC inhibitors are available, these drugs do not …

Understanding how genotypes are linked to phenotypes is important in biomedical and
evolutionary studies. The chaperone heat-shock protein 90 (HSP90) buffers genetic …

Histone deacetylase (HDAC) inhibitors, which have an effect on cell homeostasis, cell cycle
progression, and terminal differentiation, can act to promote self-renewal and enhance …

Results Sonoporation was induced by using transducer (Sonitron 2000) and, among the
several conditions tested, 3 MHz, 51% Duty Cycle, and 5 W/cm2, 30 s resulted as the best …

A disproportional large number of neurodevelopmental disorders (NDDs) is caused by
variants in genes encoding transcription factors and chromatin modifiers. However, the …

Histone deacetylase (HDAC) inhibitors promote differentiation through post-translational
modifications of histones. BML-281, an HDAC6 inhibitor, has been known to prevent tumors …

The first Jumonji gene was cloned in 1995 by Takeuchi et al.[Takeuchi T, Yamazaki Y, Katoh-
Fukui Y, Tsuchiya R, Kondo S, Motoyama J, Higashinakagawa T. Gene trap capture of a …