In Europe, with an incidence of 7.5 cases per million, Ewing sarcoma (ES) is the second
most common primary malignant bone tumor in children, adolescents and young adults …

Ewing sarcoma (ES) family of tumors includes bone and soft tissue tumors that are often
characterized by a specific translocation between chromosome 11 and 22, resulting in the …

Ewing sarcoma is a pediatric bone and soft tissue cancer with an urgent need for new
therapies to improve disease outcome. To identify effective drugs, phenotypic drug …

Ewing sarcoma (ES) is a rare aggressive cancer of bone and soft tissue that is mainly
characterized by a reciprocal chromosomal translocation. As a result, about 90% of cases …

Expression of the fusion oncoprotein EWS/FLI causes Ewing sarcoma, an aggressive
pediatric tumor characterized by widespread epigenetic deregulation. These epigenetic …

Ewing sarcoma (EwS) is a highly aggressive pediatric bone cancer that is defined by a
somatic fusion between the EWSR1 gene and an ETS family member, most frequently the …

Most cases are sporadic, but some are associated with genetic predispositions. Most
present as a painless mass and diagnosis is frequently delayed because of a low index of …

Potential New Therapies for Sarcomas: Testing the Efficacy of proteasome inhibitors
Bortezomib and Ixazomib against Ewing Sarcom Page 1 1 Potential New Therapies for …

Ewing's Sarcoma is a rare malignant tumor that grows in bones or nearby soft tissues.
Current treatment focuses on chemotherapy, radiation therapy, and surgery, yet …

Ewing sarcoma is a pediatric bone and soft tissue cancer for which new therapies to improve
disease outcome and to reduce adverse effects of current standard treatments are urgently …