SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …

Covid-19 Vaccines — Immunity, Variants, Boosters | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

Background The safety and immunogenicity of the bivalent omicron-containing mRNA-
1273.214 booster vaccine are not known. Methods In this ongoing, phase 2–3 study, we …

Immunological memory is the basis of protective immunity provided by vaccines and
previous infections. Immunological memory can develop from multiple branches of the …

Omicron Neutralization and mRNA-1273 Boosters Neutralization of the omicron variant was
assessed in serum samples obtained from persons who had received an mRNA-1273 …

The recent emergence of the SARS-CoV-2 Omicron variant is raising concerns because of
its increased transmissibility and its numerous spike mutations, which have the potential to …

Vaccination is a major tool for mitigating the coronavirus disease 2019 (COVID-19)
pandemic, and mRNA vaccines are central to the ongoing vaccination campaign that is …

The past several months have witnessed the emergence of SARS-CoV-2 variants with novel
spike protein mutations that are influencing the epidemiological and clinical aspects of the …

Background Although the three vaccines against coronavirus disease 2019 (Covid-19) that
have received emergency use authorization in the United States are highly effective …

Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …