As a full-fidelity simulation of human cells, tissues, organs, and even systems at the
microscopic scale, Organ-on-a-Chip (OOC) has significant ethical advantages and …

The approval of anticancer therapeutic strategies is still slowed down by the lack of models
able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro …

The Organ-on-a-Chip (OoC) technology shows great potential to revolutionize the drugs
development pipeline by mimicking the physiological environment and functions of human …

Bioassembly encompasses various techniques such as bioprinting, microfluidics, organoids,
and self-assembly, enabling advances in tissue engineering and regenerative medicine …

The blood–brain barrier (BBB) is an essential structure for the maintenance of brain
homeostasis. Alterations to the BBB are linked with a myriad of pathological conditions and …

The brain is arguably the most fascinating and complex organ in the human body.
Recreating the brain in vitro is an ambition restricted by our limited understanding of its …

With growing interest in neurological diseases, treatment of neurodegenerative diseases
such as Alzheimer's disease is crucial. However, drug development for nervous system …

A great progress has been made in the development and use of lab-on-a-chip devices to
model and study the blood–brain barrier (BBB) in the last decade. We present the main …

Background Recently, the safety of repeated and lengthy anesthesia administration has
been called into question, a subset of these animal studies demonstrated that anesthetics …

Physical injuries and neurodegenerative diseases often lead to irreversible damage to the
organizational structure of the central nervous system (CNS) and peripheral nervous system …