Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network
The entorhinal cortex (EC) is one of the earliest affected, most vulnerable brain regions in
Alzheimer's disease (AD), which is associated with amyloid-β (Aβ) accumulation in many …
Alzheimer's disease (AD), which is associated with amyloid-β (Aβ) accumulation in many …
A new perspective on the head direction cell system and spatial behavior
PA Dudchenko, ER Wood, A Smith - Neuroscience & Biobehavioral …, 2019 - Elsevier
The head direction cell system is an interconnected set of brain structures containing
neurons whose firing is directionally tuned. The robust representation of allocentric direction …
neurons whose firing is directionally tuned. The robust representation of allocentric direction …
Functional network of contextual and temporal memory has increased amygdala centrality and connectivity with the retrosplenial cortex, thalamus, and hippocampus
TB Santos, JC Kramer-Soares… - Scientific Reports, 2023 - nature.com
In fear conditioning with time intervals between the conditioned (CS) and unconditioned
(US) stimuli, a neural representation of the CS must be maintained over time to be …
(US) stimuli, a neural representation of the CS must be maintained over time to be …
Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology
HG Pourbadie, N Naderi, N Mehranfard, M Janahmadi… - Plos one, 2015 - journals.plos.org
The entorhinal cortex (EC) is one of the earliest affected brain regions in Alzheimer's
disease (AD). EC-amyloid pathology induces synaptic failure in the dentate gyrus (DG) with …
disease (AD). EC-amyloid pathology induces synaptic failure in the dentate gyrus (DG) with …
Evidence of temporal cortical dysfunction in rhesus monkeys following chronic cocaine self-administration
S Liu, RP Heitz, AR Sampson, W Zhang… - Cerebral …, 2008 - academic.oup.com
Cocaine abusers show impaired performance on cognitive tasks that engage prefrontal
cortex. These deficits may contribute to impaired control and relapse in abusers …
cortex. These deficits may contribute to impaired control and relapse in abusers …
Adult-onset focal expression of mutated human tau in the hippocampus impairs spatial working memory of rats
ML Mustroph, MA King, RL Klein, JJ Ramirez - Behavioural brain research, 2012 - Elsevier
Tauopathy in the hippocampus is one of the earliest cardinal features of Alzheimer's disease
(AD), a condition characterized by progressive memory impairments. In fact, density of tau …
(AD), a condition characterized by progressive memory impairments. In fact, density of tau …
Focal expression of mutated tau in entorhinal cortex neurons of rats impairs spatial working memory
JJ Ramirez, WE Poulton, E Knelson, C Barton… - Behavioural brain …, 2011 - Elsevier
Entorhinal cortex neuropathology begins very early in Alzheimer's disease (AD), a disorder
characterized by severe memory disruption. Indeed, loss of entorhinal volume is predictive …
characterized by severe memory disruption. Indeed, loss of entorhinal volume is predictive …
Delay-dependent involvement of the rat entorhinal cortex in habituation to a novel environment
T Van Cauter, B Poucet, E Save - Neurobiology of learning and memory, 2008 - Elsevier
Evidence has accumulated that the entorhinal cortex (EC) is involved in memory operations
underlying formation of a long-term memory. Because entorhinal-lesioned rats are impaired …
underlying formation of a long-term memory. Because entorhinal-lesioned rats are impaired …
Lesion-induced sprouting promotes neurophysiological integration of septal and entorhinal inputs to granule cells in the dentate gyrus of rats
MA De Niear, GR Smith, ML Robinson… - … of Learning and …, 2023 - Elsevier
Axonal sprouting of dentate gyrus (DG) afferents after entorhinal cortex (EC) lesion is a
model preparation to assess lesion-induced functional reorganization in a denervated target …
model preparation to assess lesion-induced functional reorganization in a denervated target …
Differential role of muscarinic transmission within the entorhinal cortex and basolateral amygdala in the processing of irrelevant stimuli
Cholinergic projections to the entorhinal cortex (EC) and basolateral amygdala (BLA)
mediate distinct cognitive processes through muscarinic acetylcholine receptors (mAChRs) …
mediate distinct cognitive processes through muscarinic acetylcholine receptors (mAChRs) …