53BP1 deficiency leads to hyperrecombination using break-induced replication (BIR)

SB Shah, Y Li, S Li, Q Hu, T Wu, Y Shi… - Nature …, 2024 - nature.com
Break-induced replication (BIR) is mutagenic, and thus its use requires tight regulation, yet
the underlying mechanisms remain elusive. Here we uncover an important role of 53BP1 in …

Cohesin—bridging the gap among gene transcription, genome stability, and human diseases

M Di Nardo, A Musio - FEBS letters, 2024 - Wiley Online Library
The intricate landscape of cellular processes governing gene transcription, chromatin
organization, and genome stability is a fascinating field of study. A key player in maintaining …