Biodiversity is adversely affected by the growing levels of synthetic chemicals released into
the environment due to agricultural activities. This has been the driving force for embracing …

In this review, we provide an overview of the current understanding of the main mechanisms
of pharmacological action of essential oils and their components in various biological …

Substrate inhibition of enzymes can be a major obstacle to the production of valuable
chemicals in engineered microorganisms. Here, we show substrate inhibition of lycopene …

The diterpenoid paclitaxel (Taxol) is a chemotherapy medication widely used as a first-line
treatment against several types of solid cancers. The supply of paclitaxel from natural …

For centuries, cannabis has been a rich source of fibrous, pharmaceutical, and recreational
ingredients. Phytocannabinoids are the most important and well-known class of cannabis …

Carotenoids have been related to a number of health benefits. Their dietary intake and
circulating levels have been associated with a reduced incidence of obesity, diabetes …

Rising global energy demands and climate crisis has created an unprecedented need for
the bio-based circular economy to ensure sustainable development with the minimized …

Carotenoids are natural pigments that widely exist in nature. Due to their excellent
antioxidant, anticancer and anti-inflammatory properties, carotenoids are commonly used in …

The abundant supply of biosynthetic precursors and product compatibility with the
intracellular environment play important roles for microbial isoprenoid production. In this …

Natural products account for more than 50% of all small-molecule pharmaceutical agents
currently in clinical use. However, low availability often becomes problematic when a …