Studying metabolism by NMR-based metabolomics

S Moco - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
During the past few decades, the direct analysis of metabolic intermediates in biological
samples has greatly improved the understanding of metabolic processes. The most used …

Circulating pro-and anti-inflammatory metabolites and its potential role in rheumatoid arthritis pathogenesis

R Coras, JD Murillo-Saich, M Guma - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial
joints, leading to inflammation, joint destruction, loss of function, and disability. Although …

Identifying unknown metabolites using NMR-based metabolic profiling techniques

I Garcia-Perez, JM Posma, JI Serrano-Contreras… - Nature …, 2020 - nature.com
Metabolic profiling of biological samples provides important insights into multiple
physiological and pathological processes but is hindered by a lack of automated annotation …

Integrated fecal microbiome–metabolome signatures reflect stress and serotonin metabolism in irritable bowel syndrome

Z Mujagic, M Kasapi, DMAE Jonkers, I Garcia-Perez… - Gut …, 2022 - Taylor & Francis
To gain insight into the complex microbiome-gut-brain axis in irritable bowel syndrome (IBS),
several modalities of biological and clinical data must be combined. We aimed to identify …

Fingerprinting and profiling in metabolomics of biosamples

V Ghini, G Meoni, A Vignoli, F Di Cesare… - Progress in Nuclear …, 2023 - Elsevier
This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

Current and future perspectives of functional metabolomics in disease studies–A review

M Yan, G Xu - Analytica chimica acta, 2018 - Elsevier
Functional metabolomics is a new concept, which studies the functions of metabolites and
related enzymes focused on metabolomics. It overcomes the shortcomings of traditional …

Investigation of diets associated with dilated cardiomyopathy in dogs using foodomics analysis

CE Smith, LD Parnell, CQ Lai, JE Rush… - Scientific Reports, 2021 - nature.com
Dilated cardiomyopathy (DCM) is a disease of the heart muscle that affects both humans
and dogs. Certain canine diets have been associated with DCM, but the diet-disease link is …

[HTML][HTML] A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer

S Ocvirk, AS Wilson, JM Posma, JV Li, KR Koller… - The American journal of …, 2020 - Elsevier
ABSTRACT Background Alaska Native (AN) people have the world's highest recorded
incidence of sporadic colorectal cancer (CRC)(∼ 91: 100,000), whereas rural African (RA) …

Nutriome–metabolome relationships provide insights into dietary intake and metabolism

JM Posma, I Garcia-Perez, G Frost, GS Aljuraiban… - Nature food, 2020 - nature.com
Dietary assessment traditionally relies on self-reported data, which are often inaccurate and
may result in erroneous diet–disease risk associations. We illustrate how urinary metabolic …

Recent advances in the application of metabolomics for nutrition and health

D González-Peña, L Brennan - Annual review of food science …, 2019 - annualreviews.org
Metabolomics is the study of small molecules called metabolites in biological samples.
Application of metabolomics to nutrition research has expanded in recent years, with …