Pelvic Inflammatory Disease Due to Neisseria gonorrhoeae and Chlamydia trachomatis: Immune Evasion Mechanisms and Pathogenic Disease Pathways

T Darville - The Journal of infectious diseases, 2021 - academic.oup.com
Pelvic inflammatory disease (PID) results from ascension of sexually transmitted pathogens
from the lower genital tract to the uterus and/or fallopian tubes in women, with potential …

Immune responses in the human female reproductive tract

L Monin, EM Whettlock, V Male - Immunology, 2020 - Wiley Online Library
Mucosal surfaces are key interfaces between the host and its environment, but also
constitute ports of entry for numerous pathogens. The gut and lung mucosae act as points of …

[HTML][HTML] Chlamydia trachomatis: Cell biology, immunology and vaccination

SM Murray, PF McKay - Vaccine, 2021 - Elsevier
Chlamydia trachomatis is the causative agent of a highly prevalent sexually transmitted
bacterial disease and is associated with a number of severe disease complications. Current …

Immune signature of Chlamydia vaccine CTH522/CAF® 01 translates from mouse-to-human and induces durable protection in mice

AW Olsen, I Rosenkrands, CS Jacobsen… - Nature …, 2024 - nature.com
The clinical development of an effective Chlamydia vaccine requires in-depth understanding
of how well protective pre-clinical immune signatures translate to humans. Here, we report a …

Contributions of diverse models of the female reproductive tract to the study of Chlamydia trachomatis-host interactions

FC Walker, I Derré - Current Opinion in Microbiology, 2024 - Elsevier
Highlights•Chlamydia infections have damaging consequences on female reproductive
health.•Diverse model systems are required to understand Chlamydia-host …

Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go?

LM de la Maza, TL Darville, S Pal - Expert review of vaccines, 2021 - Taylor & Francis
Introduction Chlamydia trachomatis is the most common sexually transmitted bacterial
pathogen in the world. Antibiotic treatment does not prevent against reinfection and a …

The rapid assessment of aggregated wastewater samples for genomic surveillance of SARS-CoV-2 on a city-wide scale

EC Rouchka, JH Chariker, K Saurabh, S Waigel… - Pathogens, 2021 - mdpi.com
Throughout the course of the ongoing SARS-CoV-2 pandemic there has been a need for
approaches that enable rapid monitoring of public health using an unbiased and minimally …

Cytokine profiling of samples positive for Chlamydia trachomatis and Human papillomavirus

LZA Lugo, MAM Puga, CMB Jacob, CTJ Padovani… - Plos one, 2023 - journals.plos.org
Persistent human papillomavirus (HPV) infection is closely associated with cervical
carcinoma. Co-infection in the endocervical environment with other microorganisms, such as …

Koala immunogenetics and chlamydial strain type are more directly involved in chlamydial disease progression in koalas from two south east Queensland koala …

A Robbins, J Hanger, M Jelocnik, BL Quigley… - Scientific Reports, 2020 - nature.com
Chlamydial disease control is increasingly utilised as a management tool to stabilise
declining koala populations, and yet we have a limited understanding of the factors that …

Human fallopian tube epithelial cell culture model to study host responses to Chlamydia trachomatis infection

BE McQueen, A Kiatthanapaiboon… - Infection and …, 2020 - Am Soc Microbiol
Chlamydia trachomatis infection of the human fallopian tubes can lead to damaging
inflammation and scarring, ultimately resulting in infertility. To study the human cellular …