Six3 demarcates the anterior-most developing brain region in bilaterian animals

PRH Steinmetz, R Urbach, N Posnien, J Eriksson… - EvoDevo, 2010 - Springer
Background The heads of annelids (earthworms, polychaetes, and others) and arthropods
(insects, myriapods, spiders, and others) and the arthropod-related onychophorans (velvet …

Candidate Gene Screen in the Red Flour Beetle Tribolium Reveals Six3 as Ancient Regulator of Anterior Median Head and Central Complex Development

N Posnien, NDB Koniszewski, HJ Hein… - PLoS Genetics, 2011 - journals.plos.org
Several highly conserved genes play a role in anterior neural plate patterning of vertebrates
and in head and brain patterning of insects. However, head involution in Drosophila has …

[HTML][HTML] Divergent functions of orthodenticle, empty spiracles and buttonhead in early head patterning of the beetle Tribolium castaneum (Coleoptera)

JB Schinko, N Kreuzer, N Offen, N Posnien… - Developmental …, 2008 - Elsevier
The head gap genes orthodenticle (otd), empty spiracles (ems) and buttonhead (btd) are
required for metamerization and segment specification in Drosophila. We asked whether the …

Wnt/β-catenin signaling integrates patterning and metabolism of the insect growth zone

G Oberhofer, D Grossmann, JL Siemanowski… - …, 2014 - journals.biologists.com
Wnt/β-catenin and hedgehog (Hh) signaling are essential for transmitting signals across cell
membranes in animal embryos. Early patterning of the principal insect model, Drosophila …

A clustered set of three Sp-family genes is ancestral in the Metazoa: evidence from sequence analysis, protein domain structure, developmental expression patterns …

ND Schaeper, NM Prpic, EA Wimmer - BMC evolutionary biology, 2010 - Springer
Abstract Background The Sp-family of transcription factors are evolutionarily conserved zinc
finger proteins present in many animal species. The orthology of the Sp genes in different …

The insect upper lip (labrum) is a nonsegmental appendage‐like structure

N Posnien, F Bashasab, G Bucher - Evolution & development, 2009 - Wiley Online Library
The insect upper lip—the labrum—is a lobe‐like structure anterior to the mouth opening.
Whether the labrum represents a fused pair of segmental appendages or evolved …

Functional analysis of sense organ specification in the Tribolium castaneum larva reveals divergent mechanisms in insects

M Klann, MI Schacht, MA Benton, A Stollewerk - BMC biology, 2021 - Springer
Insects and other arthropods utilise external sensory structures for mechanosensory,
olfactory, and gustatory reception. These sense organs have characteristic shapes related to …

RNAi phenotypes are influenced by the genetic background of the injected strain

P Kitzmann, J Schwirz, C Schmitt-Engel, G Bucher - BMC genomics, 2013 - Springer
Background RNA interference (RNAi) is a powerful tool to study gene function in organisms
that are not amenable to classical forward genetics. Hence, together with the ease of …

[HTML][HTML] The Tribolium ortholog of knirps and knirps-related is crucial for head segmentation but plays a minor role during abdominal patterning

AC Cerny, D Grossmann, G Bucher, M Klingler - Developmental biology, 2008 - Elsevier
Segment formation in the long germ insect Drosophila is dominated by overlapping gap
gene domains in the syncytial blastoderm. In the short germ beetle Tribolium castaneum …

[HTML][HTML] Formation of the insect head involves lateral contribution of the intercalary segment, which depends on Tc-labial function

N Posnien, G Bucher - Developmental Biology, 2010 - Elsevier
The insect head is composed of several segments. During embryonic development, the
segments fuse to form a rigid head capsule where obvious segmental boundaries are …