A comprehensive review of topoisomerase inhibitors as anticancer agents in the past decade

X Liang, Q Wu, S Luan, Z Yin, C He, L Yin, Y Zou… - European journal of …, 2019 - Elsevier
The topoisomerase enzymes play an important role in DNA metabolism, and searching for
enzyme inhibitors is an important target in the search for new anticancer drugs. Discovery of …

Secondary metabolites with biomedical applications from plants of the Sarraceniaceae family

I Miclea - International Journal of Molecular Sciences, 2022 - mdpi.com
Carnivorous plants have fascinated researchers and hobbyists for centuries because of their
mode of nutrition which is unlike that of other plants. They are able to produce bioactive …

Chemical composition, antioxidant, antitumor, anticancer and cytotoxic effects of Psidium guajava leaf extracts

A Ashraf, RA Sarfraz, MA Rashid… - Pharmaceutical …, 2016 - Taylor & Francis
Abstract Context Psidium guajava L.(Myrtaceae) leaves are used in traditional medicines for
the treatment of cancer, inflammation and other ailments. Objective The current study …

[HTML][HTML] Antioxidant and antimicrobial potential of two extracts from Capparis spinosa L. and Rumex nervosus and molecular docking investigation of selected major …

LA AlMousa, NA AlFaris, GM Alshammari… - Saudi Journal of …, 2022 - Elsevier
The present study examined the phytochemical composition, antioxidant, antimicrobial
properties, and molecular docking of different solvents extracts (methanol and water) of two …

Changes in nutrient profile and antioxidant activities of different fish soups, before and after simulated gastrointestinal digestion

G Zhang, S Zheng, Y Feng, G Shen, S Xiong, H Du - Molecules, 2018 - mdpi.com
Different kinds of freshwater fish soups show a diverse range of health functions, due to their
different nutritional substances and corresponding bioactivities. In the current study, in order …

[HTML][HTML] Chemical profiling, in vitro biological activities and Pearson correlation between chemical profiling and anticancer activities of four Abies species from Turkey

AS Yaglioglu, MS Yaglioglu, N Tosyalıoglu… - South African Journal of …, 2022 - Elsevier
Abies species are known to have various bioactive compounds and pharmacological
activities. In the manuscript, their bioactive components and anticancer activities of four …

New synthetic analogues of natural 5Z, 9Z-dienoic acids: Stereoselective synthesis and study of the anticancer activity

AA Makarov, LU Dzhemileva, AR Salimova… - Bioorganic …, 2020 - Elsevier
A stereoselective method was developed for the synthesis of synthetic analogues of natural
5Z, 9Z-dienoic acids by esterification of aliphatic and aromatic alcohols and carboxylic acids …

A comprehensive review on targeting cluster of differentiation: An attractive strategy for inhibiting viruses through host proteins

Y Zheng, J Feng, M Ling, Y Yu, Y Tao… - International Journal of …, 2024 - Elsevier
Viral infections continue to pose a significant global public health threat. Targeting host
proteins, such as cluster of differentiation (CD) macromolecules, may offer a promising …

Cytotoxic effect of Kalanchoe flammea and induction of intrinsic mitochondrial apoptotic signaling in prostate cancer cells

I Arias-González, AM García-Carrancá… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological importance Kalanchoe flammea Stapf (Crassulaceae) is a
medicinal plant grown in the South of Mexico (State of Tabasco), which is commonly used in …

Comparative Correlation Between Chemical Composition and Cytotoxic Potential of the Coral-Associated Fungus Aspergillus sp. 2C1-EGY Against Human Colon …

FK Abd El-Hady, KH Shaker, AMA Souleman… - Current …, 2017 - Springer
Cancer is a leading cause of death in several countries. In the search for new anticancer
drugs, marine organisms have played an important role in the discovery of lead compounds …