A narrative review on drug development for the management of antimicrobial-resistant infection crisis in Japan: the past, present, and future

T Ohashi, M Nagashima, N Kawai… - Expert Review of Anti …, 2022 - Taylor & Francis
Introduction Antimicrobial resistance (AMR) is a major threat to global health requiring
continuous development of new antimicrobial agents. Antimicrobial research and …

Measures against antimicrobial resistance in children in Japan: current status and future prospects

Y Kusama, N Ishiwada - The Pediatric Infectious Disease Journal, 2022 - journals.lww.com
Antimicrobial resistance (AMR) is a major problem in public health. Japan is addressing this
problem with various measures based on the National Action Plan on AMR, published in …

Improving diagnostic accuracy of blood culture-positive cases in a cancer center via an antimicrobial stewardship program and infectious disease consultations

N Itoh, N Akazawa, T Kawabata, M Yamaguchi… - Scientific Reports, 2024 - nature.com
The direct impact of antimicrobial stewardship programs (ASP) and infectious disease (ID)
consultations on patients' clinical diagnoses remains unknown. We assessed their influence …

Association between infectious diseases consultation and mortality in hospitalized patients with Gram-negative bloodstream infection: a retrospective population-wide …

SWX Ong, J Luo, DJ Fridman, SM Lee… - Clinical Infectious …, 2024 - academic.oup.com
Objectives Data supporting routine infectious diseases (ID) consultation in Gram-negative
bloodstream infection (GN-BSI) are limited. We evaluated the association between ID …

The long-term impact of an antimicrobial stewardship program in febrile neutropenia: an 8 years follow up

B Madran, Ş Keske, B Ferhanoğlu, NM Mandel… - European Journal of …, 2024 - Springer
Purpose To describe the long-term effects of an ASP among febrile neutropenia (FN)
patients. Methods A quasi-experimental study was conducted between 2015 and 2023 at a …

Exploration of trends in antimicrobial use and their determinants based on dispensing information collected from pharmacies throughout Japan: a first report

Y Muraki, M Maeda, R Inose, K Yoshimura, N Onizuka… - Antibiotics, 2022 - mdpi.com
The purpose of this study was to evaluate the defined daily doses (DDD)/1000
prescriptions/month (DPM) as a new indicator that can be used in pharmacies, and to …

Impact of an antimicrobial stewardship programme on antibiotic utilization and resistance burden in patients with acute leukaemia: an 11-year longitudinal cohort …

R Lee, D Nho, SY Cho, S Park, BS Cho… - Journal of …, 2024 - academic.oup.com
Background Antimicrobial resistance (AMR), driven by inappropriate and overuse of
antibiotics, poses a significant threat, especially to patients with acute leukaemia. Objectives …

An Overview of Selected Bacterial Infections in Cancer, Their Virulence Factors, and Some Aspects of Infection Management

A Ray, TF Moore, R Pandit, AD Burke, DM Borsch - Biology, 2023 - mdpi.com
Simple Summary Bacterial involvement in cancer can be grouped into three categories:(i)
direct association of bacteria in the processes of cancer development,(ii) secondary infection …

Efficiency of a Long-term Infectious Diseases Consultation and Antimicrobial Stewardship Program at a Japanese Cancer Center: An Interrupted Time-Series Analysis

N Itoh, N Akazawa-Kai, M Yamaguchi… - Open Forum …, 2024 - academic.oup.com
Background Patients with cancer are particularly susceptible to developing drug-resistant
organisms due to the high frequency of infections during cancer treatment and the use of …

Antibiotic spectrum coverage scoring as a potential metric for evaluating the antimicrobial stewardship team activity: a single-center study

K Oda, H Hayashi, K Yamamoto, S Kondo… - Infection Control & …, 2024 - cambridge.org
Objective: Days of antibiotic spectrum coverage (days of ASC: DASC) is a metric for
antibiotic usage calculated by ASC scores for spectrum and addresses limitations of days of …