Stroke treatment in the era of COVID-19: a review

M Simonetto, PM Wechsler, AE Merkler - Current Treatment Options in …, 2022 - Springer
Abstract Purpose of Review To describe a comprehensive review of the epidemiology,
pathophysiology, and treatment of stroke in the era of COVID-19. Recent Findings COVID-19 …

Interactions between neutrophil extracellular traps and activated platelets enhance procoagulant activity in acute stroke patients with ICA occlusion

P Zhou, T Li, J Jin, Y Liu, B Li, Q Sun, J Tian, H Zhao… - …, 2020 - thelancet.com
Background The role of neutrophil extracellular traps (NETs) in procoagulant activity (PCA)
in stroke patients caused by thromboembolic occlusion of the internal carotid artery (ICA) …

Tenecteplase versus alteplase before mechanical thrombectomy: experience from a US healthcare system undergoing a system-wide transition of primary …

P Hendrix, MK Collins, CJ Griessenauer… - Journal of …, 2023 - jnis.bmj.com
Background Tenecteplase (TNK) is a genetically modified variant of alteplase (TPA) and has
been established as a non-inferior alternative to TPA in acute ischemic stroke (AIS). Whether …

Clinical and imaging parameters associated with hyperacute infarction growth in large vessel occlusion stroke

D Puhr-Westerheide, S Tiedt, LT Rotkopf, M Herzberg… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Large vessel occlusion stroke leads to highly variable
hyperacute infarction growth. Our aim was to identify clinical and imaging parameters …

The Role of Neutrophils in Multiple Sclerosis and Ischemic Stroke

A Nowaczewska-Kuchta, D Ksiazek-Winiarek… - Brain Sciences, 2024 - mdpi.com
Inflammation plays an important role in numerous central nervous system (CNS) disorders.
Its role is ambiguous—it can induce detrimental effects, as well as repair and recovery. In …

Polygenic risk scores augment stroke subtyping

J Li, DP Chaudhary, A Khan, C Griessenauer… - Neurology …, 2021 - AAN Enterprises
Objective To determine whether the polygenic risk score (PRS) derived from MEGASTROKE
is associated with ischemic stroke (IS) and its subtypes in an independent tertiary health …

Risk factors and operative risk of large vessel occlusion and stroke during cardiac surgery

U Jain, B Jain, J Brown, J Selvakumar, I Sultan… - Journal of Stroke and …, 2024 - Elsevier
Abstract Objective Perioperative Large Vessel Occlusions (LVOs) occurring during and
following surgery are of immense clinical importance. As such, we aim to present risk factors …

Clinical criteria to exclude acute vascular pathology on CT angiogram in patients with dizziness

LH Tu, A Malhotra, AK Venkatesh, RA Taylor… - PloS one, 2023 - journals.plos.org
Background Patients presenting to the emergency department (ED) with dizziness may be
imaged via CTA head and neck to detect acute vascular pathology including large vessel …

Machine learning-based model for predicting incidence and severity of acute ischemic stroke in anterior circulation large vessel occlusion

J Cui, J Yang, K Zhang, G Xu, R Zhao, X Li… - Frontiers in …, 2021 - frontiersin.org
Objectives: Patients with anterior circulation large vessel occlusion are at high risk of acute
ischemic stroke, which could be disabling or fatal. In this study, we applied machine learning …

Replication of top loci from COL4A1/2 associated with white matter hyperintensity burden in patients with ischemic stroke

J Li, V Abedi, Regeneron Genetic Center, R Zand… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: The purpose of this study was to replicate the top loci associated
with white matter hyperintensity (WMH) phenotypes identified by large genome-wide …