MDHGI: matrix decomposition and heterogeneous graph inference for miRNA-disease association prediction

X Chen, J Yin, J Qu, L Huang - PLoS computational biology, 2018 - journals.plos.org
Recently, a growing number of biological research and scientific experiments have
demonstrated that microRNA (miRNA) affects the development of human complex diseases …

[HTML][HTML] MEF2 and the tumorigenic process, hic sunt leones

E Di Giorgio, WW Hancock, C Brancolini - Biochimica et Biophysica Acta …, 2018 - Elsevier
While MEF2 transcription factors are well known to cooperate in orchestrating cell fate and
adaptive responses during development and adult life, additional studies over the last …

The role of miRNA-223 in cancer: Function, diagnosis and therapy

Y Gao, L Lin, T Li, J Yang, Y Wei - Gene, 2017 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small, non-coding RNAs with the capacity
to regulate gene expression post-transcriptionally. miRNAs appear to hold promise of …

Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides

LY McGirt, P Jia, DA Baerenwald… - Blood, The Journal …, 2015 - ashpublications.org
The pathogenesis of mycosis fungoides (MF), the most common cutaneous T-cell lymphoma
(CTCL), is unknown. Although genetic alterations have been identified, none are considered …

MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer

MD Edmonds, KL Boyd, T Moyo, R Mitra… - The Journal of …, 2016 - Am Soc Clin Investig
MicroRNA (miR) are important regulators of gene expression, and aberrant miR expression
has been linked to oncogenesis; however, little is understood about their contribution to lung …

[HTML][HTML] MicroRNA expression profiling and DNA methylation signature for deregulated microRNA in cutaneous T-cell lymphoma

J Sandoval, A Díaz-Lagares, R Salgado… - Journal of Investigative …, 2015 - Elsevier
MicroRNAs usually regulate gene expression negatively, and aberrant expression has been
involved in the development of several types of cancers. Microarray profiling of microRNA …

Anti-Warburg effect of rosmarinic acid via miR-155 in gastric cancer cells

S Han, S Yang, Z Cai, D Pan, Z Li, Z Huang… - Drug Design …, 2015 - Taylor & Francis
Background The Warburg effect refers to glycolytic production of adenosine triphosphate
under aerobic conditions, and is a universal property of most cancer cells. Chronic …

MicroRNA expression in early mycosis fungoides is distinctly different from atopic dermatitis and advanced cutaneous T-cell lymphoma

U Ralfkiaer, L Lindal, T Litman, LM Gjerdrum… - Anticancer …, 2014 - ar.iiarjournals.org
Mycosis fungoides (MF) is the most common variant of cutaneous T-cell lymphoma (CTCL).
MF is characterized by chronic inflammation dominated by cluster of differentiation 4-positive …

[HTML][HTML] miRNA-223 is a potential diagnostic and prognostic marker for osteosarcoma

J Dong, Y Liu, W Liao, R Liu, P Shi, L Wang - Journal of bone oncology, 2016 - Elsevier
Abstract Background MicroRNA-223 (miR-223) has been shown to be a potential diagnostic
and prognostic marker for several cancers. In addition, miR-223 has been reported to …

Evidence of an oncogenic role of aberrant TOX activation in cutaneous T-cell lymphoma

Y Huang, MW Su, X Jiang… - Blood, The Journal of the …, 2015 - ashpublications.org
TOX is a nuclear factor essential for the development of CD4+ T cells in the thymus. It is
normally expressed in low amounts in mature CD4+ T cells of the skin and the peripheral …