Even at low-density lipoprotein cholesterol (LDL-C) goal, patients with cardiometabolic
abnormalities remain at high risk of cardiovascular events. This paper aims (i) to critically …

Strong experimental evidence confirms that HDL directly alleviates atherosclerosis. HDL
particles display diverse atheroprotective functions in reverse cholesterol transport (RCT) …

The inverse correlation between serum levels of high density lipoprotein (HDL) cholesterol
and the risk of coronary heart disease, the protection of susceptible animals from …

Dyslipidemia, more specifically, high-serum low-density lipoproteins and low-serum high-
density lipoproteins, are known risk factors for cardiovascular disease. The current clinical …

Low plasma levels of HDL-cholesterol (HDL-C) represent a strong and independent risk
factor for cardiovascular disease. HDL particles display a wide spectrum of atheroprotective …

OBJECTIVE—Adiponectin, synthesized in the adipose tissue, appears to play an important
role in hyperglycemia and dyslipidemia, as well as in inflammatory mechanisms, which lead …

2433 Multifunctional but Vulnerable HDL munication of results. 15 As yet, clinical and
epidemiological studies have come to discrepant and inconsistent conclusions on the …

Background—Individuals with diabetes mellitus have an increased risk of cardiovascular
disease and exhibit platelet hyperreactivity, increasing their resistance to antithrombotic …

Context: Low adiponectin levels, by regulating insulin resistance and metabolic profile, may
contribute to the markedly increased risk of atherosclerosis in diabetic subjects. Objective …

Platelets and coagulation factors are involved in the process of haemostasis, which ensures
undisturbed blood flow upon vessel wall damage. However, excessive platelet aggregation …