Deep learning-enabled virtual histological staining of biological samples

B Bai, X Yang, Y Li, Y Zhang, N Pillar… - Light: Science & …, 2023 - nature.com
Histological staining is the gold standard for tissue examination in clinical pathology and life-
science research, which visualizes the tissue and cellular structures using chromatic dyes or …

[HTML][HTML] Stain normalization methods for histopathology image analysis: A comprehensive review and experimental comparison

MZ Hoque, A Keskinarkaus, P Nyberg, T Seppänen - Information Fusion, 2024 - Elsevier
The advent of whole slide imaging has brought advanced computer-aided diagnosis via
medical imaging and artificial intelligence technologies in digital pathology. The …

Deconv-transformer (DecT): A histopathological image classification model for breast cancer based on color deconvolution and transformer architecture

Z He, M Lin, Z Xu, Z Yao, H Chen, A Alhudhaif… - Information …, 2022 - Elsevier
Histopathological image recognition of breast cancer is an onerous task. Although many
deep learning models have achieved good classification results on histopathological image …

Development of an end-to-end deep learning framework for sign language recognition, translation, and video generation

B Natarajan, E Rajalakshmi, R Elakkiya… - IEEE …, 2022 - ieeexplore.ieee.org
The recent developments in deep learning techniques evolved to new heights in various
domains and applications. The recognition, translation, and video generation of Sign …

Virtual birefringence imaging and histological staining of amyloid deposits in label-free tissue using autofluorescence microscopy and deep learning

X Yang, B Bai, Y Zhang, M Aydin, Y Li… - Nature …, 2024 - nature.com
Systemic amyloidosis involves the deposition of misfolded proteins in organs/tissues,
leading to progressive organ dysfunction and failure. Congo red is the gold-standard …

Accelerating histopathology workflows with generative AI-based virtually multiplexed tumour profiling

P Pati, S Karkampouna, F Bonollo… - Nature Machine …, 2024 - nature.com
Understanding the spatial heterogeneity of tumours and its links to disease initiation and
progression is a cornerstone of cancer biology. Presently, histopathology workflows heavily …

Multistain Pretraining for Slide Representation Learning in Pathology

G Jaume, A Vaidya, A Zhang, AH Song… - … on Computer Vision, 2025 - Springer
Developing self-supervised learning (SSL) models that can learn universal and transferable
representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly …

Virtual stain transfer in histology via cascaded deep neural networks

X Yang, B Bai, Y Zhang, Y Li, K de Haan, T Liu… - ACS …, 2022 - ACS Publications
Pathological diagnosis relies on the visual inspection of histologically stained thin tissue
specimens, where different types of stains are applied to bring contrast to and highlight …

[HTML][HTML] Unstained tissue imaging and virtual hematoxylin and eosin staining of histologic whole slide images

S Koivukoski, U Khan, P Ruusuvuori, L Latonen - Laboratory Investigation, 2023 - Elsevier
Tissue structures, phenotypes, and pathology are routinely investigated based on histology.
This includes chemically staining the transparent tissue sections to make them visible to the …

[HTML][HTML] AI-driven 3D bioprinting for regenerative medicine: from bench to bedside

Z Zhang, X Zhou, Y Fang, Z Xiong, T Zhang - Bioactive Materials, 2025 - Elsevier
In recent decades, 3D bioprinting has garnered significant research attention due to its
ability to manipulate biomaterials and cells to create complex structures precisely. However …