[PDF][PDF] Disruption of the blood brain barrier is vital property of neurotropic viral infection of the central nervous system
The blood brain barrier consisting of astrocytes, pericytes and brain microvascular
endothelial cells plays a vital role in the pathogenesis of neurotropic viruses by controlling …
endothelial cells plays a vital role in the pathogenesis of neurotropic viruses by controlling …
Axl mediates ZIKA virus entry in human glial cells and modulates innate immune responses
L Meertens, A Labeau, O Dejarnac, S Cipriani… - Cell reports, 2017 - cell.com
ZIKA virus (ZIKV) is an emerging pathogen responsible for neurological disorders and
congenital microcephaly. However, the molecular basis for ZIKV neurotropism remains …
congenital microcephaly. However, the molecular basis for ZIKV neurotropism remains …
Human fetal tissue is critical for biomedical research
Human fetal tissue and cells derived from fetal tissue are crucial for biomedical research.
Fetal tissues and cells are used to study both normal development and developmental …
Fetal tissues and cells are used to study both normal development and developmental …
Zika virus strains potentially display different infectious profiles in human neural cells
The recent Zika virus (ZIKV) epidemic has highlighted the poor knowledge on its
physiopathology. Recent studies showed that ZIKV of the Asian lineage, responsible for this …
physiopathology. Recent studies showed that ZIKV of the Asian lineage, responsible for this …
Zika virus disrupts molecular fingerprinting of human neurospheres
PP Garcez, JM Nascimento, JM de Vasconcelos… - Scientific reports, 2017 - nature.com
Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities;
however, the molecular consequences of ZIKV to human brain development are still not fully …
however, the molecular consequences of ZIKV to human brain development are still not fully …
[HTML][HTML] Zika antiviral chemotherapy: identification of drugs and promising starting points for drug discovery from an FDA-approved library
BS Pascoalino, G Courtemanche, MT Cordeiro… - …, 2016 - ncbi.nlm.nih.gov
Background The recent epidemics of Zika virus (ZIKV) implicated it as the cause of serious
and potentially lethal congenital conditions such microcephaly and other central nervous …
and potentially lethal congenital conditions such microcephaly and other central nervous …
Development of a high-throughput colorimetric Zika virus infection assay
Zika virus (ZIKV) is an emerging pathogen that causes congenital infections which may
result in birth defects, such as microcephaly. Currently, no approved treatment or vaccination …
result in birth defects, such as microcephaly. Currently, no approved treatment or vaccination …
[HTML][HTML] Replication of the Zika virus in different iPSC-derived neuronal cells and implications to assess efficacy of antivirals
Infections with the Zika virus (ZIKV) are responsible for congenital abnormalities and
neurological disorders. We here demonstrate that ZIKV productively infects three types of …
neurological disorders. We here demonstrate that ZIKV productively infects three types of …
[HTML][HTML] Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barré syndrome: From systematic review to living systematic review
MJ Counotte, D Egli-Gany, M Riesen, M Abraha… - …, 2018 - ncbi.nlm.nih.gov
Background. The Zika virus (ZIKV) outbreak in the Americas has caused international
concern due to neurological sequelae linked to the infection, such as microcephaly and …
concern due to neurological sequelae linked to the infection, such as microcephaly and …
Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes
J Sun, W Zhang, Z Tan, C Zheng, Y Tang, X Ke… - Virulence, 2020 - Taylor & Francis
Zika virus (ZIKV) infection in the human central nervous system (CNS) causes Guillain–
Barre syndrome, cerebellum deformity, and other diseases. Astrocytes are immune …
Barre syndrome, cerebellum deformity, and other diseases. Astrocytes are immune …