S Gelman, SA Fahlberg… - Proceedings of the …, 2021 - National Acad Sciences
The mapping from protein sequence to function is highly complex, making it challenging to predict how sequence changes will affect a protein's behavior and properties. We present a …
Data-driven strategies are gaining increased attention in protein engineering due to recent advances in access to large experimental databanks of proteins, next-generation …
Protein language models trained on evolutionary data have emerged as powerful tools for predictive problems involving protein sequence, structure, and function. However, these …
T Lu, AX Lu, AM Moses - arXiv preprint arXiv:2104.14661, 2021 - arxiv.org
Large self-supervised models pretrained on millions of protein sequences have recently gained popularity in generating embeddings of protein sequences for protein function …