Emotion processing dysfunction in Alzheimer's disease: an overview of behavioral findings, systems neural correlates, and underlying neural biology

S Chaudhary, S Zhornitsky, HH Chao… - American Journal of …, 2022 - journals.sagepub.com
We described behavioral studies to highlight emotional processing deficits in Alzheimer's
disease (AD). The findings suggest prominent deficit in recognizing negative emotions …

LRP1 and RAGE Genes Transporting Amyloid and Tau Protein in the Hippocampal CA3 Area in an Ischemic Model of Alzheimer's Disease with 2-Year Survival

R Pluta, J Kocki, J Bogucki, A Bogucka-Kocka… - Cells, 2023 - mdpi.com
Explaining changes at the gene level that occur during neurodegeneration in the CA3 area
is crucial from the point of view of memory impairment and the development of post-ischemic …

MR‐based spatiotemporal anisotropic atrophy evaluation of hippocampus in Alzheimer's disease progression by multiscale skeletal representation

N Gao, Z Liu, Y Deng, H Chen, C Ye… - Human Brain …, 2023 - Wiley Online Library
Increasing evidence has shown a higher sensitivity of Alzheimer's disease (AD) progression
by local hippocampal atrophy rather than the whole volume. However, existing …

Volume changes of hippocampal and amygdala subfields in patients with mild cognitive impairment and Alzheimer's disease

H Qu, H Ge, L Wang, W Wang, C Hu - Acta Neurologica Belgica, 2023 - Springer
Background Automated segmentation of hippocampal and amygdala subfields could
improve classification accuracy of Mild Cognitive Impairments (MCI) and Alzheimer's …

[HTML][HTML] Neuropsychological profiles and neural correlates in typical and atypical variants of Alzheimer disease: A systematic qualitative review

C Fredes-Roa, F Gutiérrez-Barría… - Neurology …, 2023 - Elsevier
Introduction Neuropsychological symptoms and cortical atrophy patterns show similarities
between typical Alzheimer's Disease (AD) and its variants. Thus, correct diagnosis is difficult …

Posterior cortical atrophy: Primary occipital variant

D Shir, J Graff‐Radford, MM Machulda… - European journal of …, 2022 - Wiley Online Library
Background Posterior cortical atrophy (PCA) is one of the atypical Alzheimer's disease
variants, characterized by predominant visuospatial and visuoperceptual deficits, with …

APOE ε4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease

NA Singh, N Tosakulwong… - Alzheimer's & …, 2023 - Wiley Online Library
Abstract Introduction Apolipoprotein E (APOE) ε4 is an important genetic risk factor for typical
Alzheimer's disease (AD), influencing brain volume and tau burden. Little is known about its …

Medial temporal atrophy in posterior cortical atrophy and its relationship to the cingulate island sign

KA Josephs, NTT Pham, J Graff-Radford… - Journal of …, 2022 - content.iospress.com
Background: It has been hypothesized that medial temporal sparing may be related to
preserved posterior cingulate metabolism and the cingulate island sign (CIS) on [18 F] …

MRI‐based axis‐referenced morphometric model corresponding to lamellar organization for assessing hippocampal atrophy in dementia

N Gao, C Ye, H Chen, X Hao, T Ma - Human Brain Mapping, 2024 - Wiley Online Library
Research on the local hippocampal atrophy for early detection of dementia has gained
considerable attention. However, accurately quantifying subtle atrophy remains challenging …

Hippocampal subfield volume in older adults with and without mild cognitive impairment: effects of worry and cognitive reappraisal

HT Karim, S Lee, A Gerlach, M Stinley, R Berta… - Neurobiology of …, 2024 - Elsevier
Studies have confirmed that anxiety, especially worry and rumination, are associated with
increased risk for cognitive decline, including Alzheimer's disease and related dementias …